Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations - Test2 - elhamkhani - TriplyDB

Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations

Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations

http://www.wikidata.org/entity/Q30491040

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Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model.Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline Effects of synaptic modulation on beta-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice.Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo Cholesterol in the Pathogenesis of Alzheimer's, Parkinson's Diseases and Autism: Link to Synaptic Dysfunction Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression.The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease.Synapses, synaptic activity and intraneuronal abeta in Alzheimer's disease.Probing the biology of Alzheimer's disease in mice.Mitochondrial dysfunction and cellular metabolic deficiency in Alzheimer's disease Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease.More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration Apomorphine and Alzheimer Aβ: roles for regulated α cleavage, autophagy, and antioxidation?Is brain amyloid production a cause or a result of dementia of the Alzheimer's type?Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease.Impaired β-amyloid secretion in Alzheimer's disease pathogenesis.PKMζ, but not PKCλ, is rapidly synthesized and degraded at the neuronal synapse.Amyloid β: linking synaptic plasticity failure to memory disruption in Alzheimer's disease Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease.Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease.Synaptic activity and Alzheimer's disease: a critical update.Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects.Critical role of intraneuronal Aβ in Alzheimer's disease: technical challenges in studying intracellular Aβ.Neuronal activity and secreted amyloid β lead to altered amyloid β precursor protein and presenilin 1 interactions Early enriched environment exposure protects spatial memory and accelerates amyloid plaque formation in APP(Swe)/PS1(L166P) mice.Soluble adenylyl cyclase is essential for proper lysosomal acidification Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP.Therapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option?The influence of synaptic activity on neuronal health.Synapses, NMDA receptor activity and neuronal Aβ production in Alzheimer's disease.Protein aggregate spreading in neurodegenerative diseases: problems and perspectives New therapeutic targets in Alzheimer's disease: brain deregulation of calcium and zinc.Hippocampal synaptic plasticity in Alzheimer's disease: what have we learned so far from transgenic models?Consequences of inhibiting amyloid precursor protein processing enzymes on synaptic function and plasticity.Developmental neuroplasticity and the origin of neurodegenerative diseases.

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P2860

Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations

http://www.wikidata.org/entity/Q30491040

description

2009 nî lūn-bûn

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2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի օգոստոսին հրատարակված գիտական հոդված

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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name

Synaptic activity reduces intr ...... a-related synaptic alterations

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Synaptic activity reduces intr ...... a-related synaptic alterations

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Synaptic activity reduces intr ...... a-related synaptic alterations

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Synaptic activity reduces intr ...... a-related synaptic alterations

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Synaptic activity reduces intr ...... a-related synaptic alterations

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JNEUROSCI.2292-09.2009

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Journal of Neuroscience

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Synaptic activity reduces intr ...... a-related synaptic alterations

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Bao Lu

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David M Nanus

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Davide Tampellini

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Eduardo F Gallo

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Estibaliz Capetillo-Zarate

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Magali Dumont

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Michael T Lin

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Nawreen Rahman

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Rong Zheng

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Tao Ma

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P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticity

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology

Regulation of NMDA receptor trafficking by amyloid-beta

Activity-dependent dynamics and sequestration of proteasomes in dendritic spines

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus.

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9704-9713

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10.1523/JNEUROSCI.2292-09.2009

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26719199

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