Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae.
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General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADHDeletion of FPS1, encoding aquaglyceroporin Fps1p, improves xylose fermentation by engineered Saccharomyces cerevisiae.Metabolic engineering for improved microbial pentose fermentationProtein engineering in designing tailored enzymes and microorganisms for biofuels productionBulk segregant analysis by high-throughput sequencing reveals a novel xylose utilization gene from Saccharomyces cerevisiaeIdentification of novel metabolic interactions controlling carbon flux from xylose to ethanol in natural and recombinant yeasts.Stepwise metabolic adaption from pure metabolization to balanced anaerobic growth on xylose explored for recombinant Saccharomyces cerevisiae.Limitations in xylose-fermenting Saccharomyces cerevisiae, made evident through comprehensive metabolite profiling and thermodynamic analysisFermentation of mixed glucose-xylose substrates by engineered strains of Saccharomyces cerevisiae: role of the coenzyme specificity of xylose reductase, and effect of glucose on xylose utilization.Increased ethanol productivity in xylose-utilizing Saccharomyces cerevisiae via a randomly mutagenized xylose reductase.Engineering redox homeostasis to develop efficient alcohol-producing microbial cell factories.Xylose reductase from the thermophilic fungus Talaromyces emersonii: cloning and heterologous expression of the native gene (Texr) and a double mutant (TexrK271R + N273D) with altered coenzyme specificity.Bioconversion of lignocellulose-derived sugars to ethanol by engineered Saccharomyces cerevisiae.Process intensification through microbial strain evolution: mixed glucose-xylose fermentation in wheat straw hydrolyzates by three generations of recombinant Saccharomyces cerevisiaeRational and evolutionary engineering approaches uncover a small set of genetic changes efficient for rapid xylose fermentation in Saccharomyces cerevisiaeFrom wheat straw to bioethanol: integrative analysis of a separate hydrolysis and co-fermentation process with implemented enzyme production.Cofermentation of glucose, xylose, and cellobiose by the beetle-associated yeast Spathaspora passalidarum.Balance of XYL1 and XYL2 expression in different yeast chassis for improved xylose fermentation.Genome sequence and physiological analysis of Yamadazyma laniorum f.a. sp. nov. and a reevaluation of the apocryphal xylose fermentation of its sister species, Candida tenuis.Growth and fermentation of D-xylose by Saccharomyces cerevisiae expressing a novel D-xylose isomerase originating from the bacterium Prevotella ruminicola TC2-24.Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae.Pichia stipitis genomics, transcriptomics, and gene clustersEthanol production from xylose in engineered Saccharomyces cerevisiae strains: current state and perspectives.Biotechnological production and applications of N-acetyl-D-neuraminic acid: current state and perspectives.Plant cell walls to ethanol.Protein design in systems metabolic engineering for industrial strain development.Metabolic engineering strategies for improving xylitol production from hemicellulosic sugars.Recent advances in rational approaches for enzyme engineering.Genetic improvement of native xylose-fermenting yeasts for ethanol production.Point mutation of the xylose reductase (XR) gene reduces xylitol accumulation and increases citric acid production in Aspergillus carbonarius.A design-build-test cycle using modeling and experiments reveals interdependencies between upper glycolysis and xylose uptake in recombinant S. cerevisiae and improves predictive capabilities of large-scale kinetic modelsDecreased xylitol formation during xylose fermentation in Saccharomyces cerevisiae due to overexpression of water-forming NADH oxidase.Saccharomyces cerevisiae strain comparison in glucose-xylose fermentations on defined substrates and in high-gravity SSCF: convergence in strain performance despite differences in genetic and evolutionary engineering history.13C-Metabolic Flux Analysis: An Accurate Approach to Demystify Microbial Metabolism for Biochemical Production.Analysis and prediction of the physiological effects of altered coenzyme specificity in xylose reductase and xylitol dehydrogenase during xylose fermentation by Saccharomyces cerevisiae.Arabinose and xylose fermentation by recombinant Saccharomyces cerevisiae expressing a fungal pentose utilization pathway.Accumulation of metabolic side products might favor the production of ethanol in Pho13 knockout strains.Comparison of Scheffersomyces stipitis strains CBS 5773 and CBS 6054 with regard to their xylose metabolism: implications for xylose fermentationEngineering of xylose reductase and overexpression of xylitol dehydrogenase and xylulokinase improves xylose alcoholic fermentation in the thermotolerant yeast Hansenula polymorpha.Yeast cell factory: fishing for the best one or engineering it?
P2860
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P2860
Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Altering the coenzyme preferen ...... n of Saccharomyces cerevisiae.
@ast
Altering the coenzyme preferen ...... n of Saccharomyces cerevisiae.
@en
type
label
Altering the coenzyme preferen ...... n of Saccharomyces cerevisiae.
@ast
Altering the coenzyme preferen ...... n of Saccharomyces cerevisiae.
@en
prefLabel
Altering the coenzyme preferen ...... n of Saccharomyces cerevisiae.
@ast
Altering the coenzyme preferen ...... n of Saccharomyces cerevisiae.
@en
P2860
P356
P1476
Altering the coenzyme preferen ...... n of Saccharomyces cerevisiae.
@en
P2093
Barbara Petschacher
P2860
P2888
P356
10.1186/1475-2859-7-9
P577
2008-03-17T00:00:00Z
P5875
P6179
1031410646