Malaria parasite actin polymerization and filament structure
about
Evolutionarily divergent, unstable filamentous actin is essential for gliding motility in apicomplexan parasitesCorrelative nanoscale imaging of actin filaments and their complexesSpatial localisation of actin filaments across developmental stages of the malaria parasiteStructural differences explain diverse functions of Plasmodium actinsAn Unroofing Method to Observe the Cytoskeleton Directly at Molecular Resolution Using Atomic Force Microscopy.Role of calcineurin and actin dynamics in regulated secretion of microneme proteins in Plasmodium falciparum merozoites during erythrocyte invasionPlasmodium falciparum aldolase and the C-terminal cytoplasmic domain of certain apical organellar proteins promote actin polymerizationPivotal and distinct role for Plasmodium actin capping protein alpha during blood infection of the malaria parasitePlasmodium falciparum coronin organizes arrays of parallel actin filaments potentially guiding directional motility in invasive malaria parasitesHigh-frequency multimodal atomic force microscopy.The unusual dynamics of parasite actin result from isodesmic polymerization.Single-molecule imaging and kinetic analysis of cooperative cofilin-actin filament interactionsPlasmodium actin is incompletely folded by heterologous protein-folding machinery and likely requires the native Plasmodium chaperonin complex to enter a mature functional state.A unique profilin-actin interface is important for malaria parasite motilityEffect of envelope proteins on the mechanical properties of influenza virusCofilin-induced unidirectional cooperative conformational changes in actin filaments revealed by high-speed atomic force microscopy.Defining the morphology and mechanism of the hemoglobin transport pathway in Plasmodium falciparum-infected erythrocytes.Swelling and softening of the cowpea chlorotic mottle virus in response to pH shiftsCritical role for heat shock protein 20 (HSP20) in migration of malarial sporozoites.Direct observation of the actin filament by tip-scan atomic force microscopy.Holding back the microfilament--structural insights into actin and the actin-monomer-binding proteins of apicomplexan parasites.Towards a molecular understanding of the apicomplexan actin motor: on a road to novel targets for malaria remedies?Drebrin-like protein DBN-1 is a sarcomere component that stabilizes actin filaments during muscle contraction.Demonstration of correlative atomic force and transmission electron microscopy using actin cytoskeleton.Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability.Geometrical model for malaria parasite migration in structured environments.Crystallization and preliminary structural characterization of the two actin isoforms of the malaria parasite.Apicomplexan actin polymerization depends on nucleation.Genetic crosses and complementation reveal essential functions for the Plasmodium stage-specific actin2 in sporogonic development.Stage-specific depletion of myosin A supports an essential role in motility of malarial ookinetes.Inter-subunit interactions drive divergent dynamics in mammalian and Plasmodium actin filaments
P2860
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P2860
Malaria parasite actin polymerization and filament structure
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Malaria parasite actin polymerization and filament structure
@ast
Malaria parasite actin polymerization and filament structure
@en
type
label
Malaria parasite actin polymerization and filament structure
@ast
Malaria parasite actin polymerization and filament structure
@en
prefLabel
Malaria parasite actin polymerization and filament structure
@ast
Malaria parasite actin polymerization and filament structure
@en
P2093
P2860
P50
P356
P1476
Malaria parasite actin polymerization and filament structure
@en
P2093
Claudia Veigel
Lesley Calder
Munira Grainger
Peter B Rosenthal
Simone Harder
Stephan Schmitz
P2860
P304
36577-36585
P356
10.1074/JBC.M110.142638
P407
P577
2010-09-07T00:00:00Z