Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement.
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Pathogenic mechanisms in centronuclear myopathiesRefilinB (FAM101B) targets filamin A to organize perinuclear actin networks and regulates nuclear shape.Nuclear positioning by actin cables and perinuclear actin: Special and general?Putative biomarkers and targets of estrogen receptor negative human breast cancerThe nuclear envelope: an intriguing focal point for neurogenetic diseaseLinker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts.Nuclear deformability and telomere dynamics are regulated by cell geometric constraints.Cytoskeletal tension induces the polarized architecture of the nucleus.Nuclear migration events throughout developmentImplications and Assessment of the Elastic Behavior of Lamins in LaminopathiesNew approaches for understanding the nuclear force balance in living, adherent cellsMuscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organizationNucleocytoplasmic connections and deafness.The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton.The nucleus of endothelial cell as a sensor of blood flow directionEmerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts.Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus.Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration.Inner nuclear membrane proteins: impact on human disease.Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environmentsAccessorizing and anchoring the LINC complex for multifunctionality.Orientation and function of the nuclear-centrosomal axis during cell migration.Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neuronsThe nucleus is an intracellular propagator of tensile forces in NIH 3T3 fibroblasts.Analysis of tubulin alpha-1A/1B C-terminal tail post-translational poly-glutamylation reveals novel modification sites.Nuclear membrane diversity: underlying tissue-specific pathologies in disease?The functions of the nuclear envelope in mediating the molecular crosstalk between the nucleus and the cytoplasm.Lamins at a glance.Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function.The cellular mastermind(?)-mechanotransduction and the nucleus.Nuclear mechanics in cancerCellular stress induces Bax-regulated nuclear bubble budding and rupture followed by nuclear protein releaseAltered chromatin organization and SUN2 localization in mandibuloacral dysplasia are rescued by drug treatment.Structural organization of nuclear lamins A, C, B1, and B2 revealed by superresolution microscopy.Force-induced changes in subnuclear movement and rheology.Lamin A/C deficiency reduces circulating tumor cell resistance to fluid shear stressConnecting the nucleus to the cytoskeleton by SUN-KASH bridges across the nuclear envelope.Nuclear positioning.
P2860
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P2860
Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Lamin A variants that cause st ...... ar lines for nuclear movement.
@ast
Lamin A variants that cause st ...... ar lines for nuclear movement.
@en
type
label
Lamin A variants that cause st ...... ar lines for nuclear movement.
@ast
Lamin A variants that cause st ...... ar lines for nuclear movement.
@en
prefLabel
Lamin A variants that cause st ...... ar lines for nuclear movement.
@ast
Lamin A variants that cause st ...... ar lines for nuclear movement.
@en
P2093
P2860
P921
P356
P1476
Lamin A variants that cause st ...... ear lines for nuclear movement
@en
P2093
Cecilia Ostlund
Eric S Folker
Gregg G Gundersen
Howard J Worman
P2860
P304
P356
10.1073/PNAS.1000824108
P407
P577
2010-12-20T00:00:00Z