The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton
about
Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutationsLRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors.Both contractile axial and lateral traction force dynamics drive amoeboid cell motilityRAB1A promotes Vaccinia virus replication by facilitating the production of intracellular enveloped virions.The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins.Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP.Leucine-rich repeat kinase 2 and alternative splicing in Parkinson's disease.
P2860
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P2860
The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton
description
2011 nî lūn-bûn
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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
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2011年の論文
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2011年学术文章
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2011年学术文章
@zh-cn
2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
The LRRK2-related Roco kinase ...... ontrols the actin cytoskeleton
@ast
The LRRK2-related Roco kinase ...... ontrols the actin cytoskeleton
@en
type
label
The LRRK2-related Roco kinase ...... ontrols the actin cytoskeleton
@ast
The LRRK2-related Roco kinase ...... ontrols the actin cytoskeleton
@en
prefLabel
The LRRK2-related Roco kinase ...... ontrols the actin cytoskeleton
@ast
The LRRK2-related Roco kinase ...... ontrols the actin cytoskeleton
@en
P2093
P2860
P356
P1476
The LRRK2-related Roco kinase ...... ontrols the actin cytoskeleton
@en
P2093
Richard A Firtel
Sebastian Kicka
Steven Briggs
Zhouxin Shen
P2860
P304
P356
10.1091/MBC.E10-12-0937
P577
2011-05-05T00:00:00Z