about
Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activitiesNeurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanismsNormal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factorDistribution, recognition and regulation of non-CpG methylation in the adult mammalian brain.Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells.Variations of X chromosome inactivation occur in early passages of female human embryonic stem cellsRepression of retrotransposal elements in mouse embryonic stem cells is primarily mediated by a DNA methylation-independent mechanism.Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells.Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing.A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesisEvaluation of x-inactivation status and cytogenetic stability of human dermal fibroblasts after long-term culture.The ligase PIAS1 restricts natural regulatory T cell differentiation by epigenetic repressionThe role of DNA methylation in the central nervous system and neuropsychiatric disorders.A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samplesJuvenile neurogenesis makes essential contributions to adult brain structure and plays a sex-dependent role in fear memories.Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation.Methyl-CpG binding proteins in the nervous system.Dnmt3a regulates both proliferation and differentiation of mouse neural stem cellsRole of Tet1 and 5-hydroxymethylcytosine in cocaine action.Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.Hydrogel matrix to support stem cell survival after brain transplantation in stroke.CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain.Dnmt1-dependent DNA methylation is essential for photoreceptor terminal differentiation and retinal neuron survivalX-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterationsIdentification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells.Epigenetic regulation of neural gene expression and neuronal function.Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cellsDNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturationEpigenetic regulation of X-inactivation in human embryonic stem cells.Copy number variant analysis of human embryonic stem cells.X chromosome inactivation in human and mouse pluripotent stem cells.DNA methylation in cell differentiation and reprogramming: an emerging systematic view.DNA methylation and its basic function.Polyethylene glycol-based protein nanocapsules for functional delivery of a differentiation transcription factor.Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx.Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells.Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity.Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells.A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells.
P50
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P50
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wetenschapper
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հետազոտող
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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Guoping Fan
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P106
P1153
7202775571
P31
P496
0000-0001-5235-6410