PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling. - Test2 - elhamkhani - TriplyDB

PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling.

PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling.

http://www.wikidata.org/entity/Q30503120

about

Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart Elevated expression of the integrin-associated protein PINCH suppresses the defects of Drosophila melanogaster muscle hypercontraction mutants Alterations in cardiac DNA methylation in human dilated cardiomyopathy Integrins and integrin-associated proteins in the cardiac myocyte.RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish.Overlapping and opposing functions of G protein-coupled receptor kinase 2 (GRK2) and GRK5 during heart development.Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish.Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis.β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses.LNK (SH2B3) is a key regulator of integrin signaling in endothelial cells and targets α-parvin to control cell adhesion and migration.A crucial role for Ras suppressor-1 (RSU-1) revealed when PINCH and ILK binding is disrupted.Loss of the AE3 Cl(-)/HCO(-) 3 exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart.The zebrafish model system in cardiovascular research: A tiny fish with mighty prospects.Zebrafish models in cardiac development and congenital heart birth defects.High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains.LIMS2 mutations are associated with a novel muscular dystrophy, severe cardiomyopathy and triangular tongues.Integrin-linked kinase mediates force transduction in cardiomyocytes by modulating SERCA2a/PLN function.Cardiac shock wave therapy promotes arteriogenesis of coronary micrangium, and ILK is involved in the biomechanical effects by proteomic analysis.

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PINCH proteins regulate cardiac contractility by modulating integrin-linked kinase-protein kinase B signaling.

http://www.wikidata.org/entity/Q30503120

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

PINCH proteins regulate cardia ...... se-protein kinase B signaling.

@ast

PINCH proteins regulate cardia ...... se-protein kinase B signaling.

@en

type

label

PINCH proteins regulate cardia ...... se-protein kinase B signaling.

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PINCH proteins regulate cardia ...... se-protein kinase B signaling.

@en

prefLabel

PINCH proteins regulate cardia ...... se-protein kinase B signaling.

@ast

PINCH proteins regulate cardia ...... se-protein kinase B signaling.

@en

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Molecular and Cellular Biology

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PINCH proteins regulate cardia ...... ase-protein kinase B signaling

@en

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Benjamin Meder

http://www.w3.org/2001/XMLSchema#string

Britta Vogel

http://www.w3.org/2001/XMLSchema#string

Doreen Köhler

http://www.w3.org/2001/XMLSchema#string

Farbod Sedaghat-Hamedani

http://www.w3.org/2001/XMLSchema#string

Hugo A Katus

http://www.w3.org/2001/XMLSchema#string

Inken G Huttner

http://www.w3.org/2001/XMLSchema#string

Jessica Rudloff

http://www.w3.org/2001/XMLSchema#string

Karen S Frese

http://www.w3.org/2001/XMLSchema#string

Sabine Marquart

http://www.w3.org/2001/XMLSchema#string

Steffen Just

http://www.w3.org/2001/XMLSchema#string

P2860

A new LIM protein containing an autoepitope homologous to "senescent cell antigen"

Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

Integrin-linked kinase is an adaptor with essential functions during mouse development

Role of the integrin-linked kinase/PINCH1/alpha-parvin complex in cardiac myocyte hypertrophy

Targeted ablation of PINCH1 and PINCH2 from murine myocardium results in dilated cardiomyopathy and early postnatal lethality

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3424-3435

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scholarly article

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10.1128/MCB.05269-11

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16

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31

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2011-06-13T00:00:00Z

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21670146

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3147799

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