Mitochondrial superoxide flashes: metabolic biomarkers of skeletal muscle activity and disease - Test2 - elhamkhani - TriplyDB

Mitochondrial superoxide flashes: metabolic biomarkers of skeletal muscle activity and disease

Mitochondrial superoxide flashes: metabolic biomarkers of skeletal muscle activity and disease

http://www.wikidata.org/entity/Q30503539

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Pulsing of membrane potential in individual mitochondria: a stress-induced mechanism to regulate respiratory bioenergetics in Arabidopsis Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish Proinflammatory Cytokines Stimulate Mitochondrial Superoxide Flashes in Articular Chondrocytes In Vitro and In Situ Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling LIPCAR: a mitochondrial lnc in the noncoding RNA chain?Orai1-dependent calcium entry promotes skeletal muscle growth and limits fatigue OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange Mitochondrial fusion is frequent in skeletal muscle and supports excitation-contraction coupling Regulation of metabolism in individual mitochondria during excitation-contraction coupling Regulation of Mitoflash Biogenesis and Signaling by Mitochondrial Dynamics.Absence of physiological Ca2+ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation.Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity.Mitochondrial flashes regulate ATP homeostasis in the heart.Confocal imaging of single mitochondrial superoxide flashes in intact heart or in vivo The evolution of the mitochondria-to-calcium release units relationship in vertebrate skeletal muscles.Oxidative stress, mitochondrial damage, and cores in muscle from calsequestrin-1 knockout mice AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.Superoxide flashes reveal novel properties of mitochondrial reactive oxygen species excitability in cardiomyocytes.Oxidative stress and successful antioxidant treatment in models of RYR1-related myopathy Antioxidants protect calsequestrin-1 knockout mice from halothane- and heat-induced sudden death.Perspectives on: SGP symposium on mitochondrial physiology and medicine: mitochondrial superoxide flashes: from discovery to new controversies Mitoflash altered by metabolic stress in insulin-resistant skeletal muscle.Physiological and pathological roles of the mitochondrial permeability transition pore in the heart.Mitochondrial flash as a novel biomarker of mitochondrial respiration in the heart.Age-dependent uncoupling of mitochondria from Ca2⁺ release units in skeletal muscle.Synergistic triggering of superoxide flashes by mitochondrial Ca2+ uniport and basal reactive oxygen species elevation.Respective contribution of mitochondrial superoxide and pH to mitochondria-targeted circularly permuted yellow fluorescent protein (mt-cpYFP) flash activity.Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca²⁺ and reactive oxygen species signaling.Imaging ROS signaling in cells and animals.Protons Trigger Mitochondrial Flashes Mitochondrial Flash: Integrative Reactive Oxygen Species and pH Signals in Cell and Organelle Biology.L-OPA1 regulates mitoflash biogenesis independently from membrane fusion.The disorders of the calcium release unit of skeletal muscles: what have we learned from mouse models?Imaging mitochondrial reactive oxygen species with fluorescent probes: current applications and challenges.Modeling cell response to low doses of photon irradiation: Part 2--application to radiation-induced chromosomal aberrations in human carcinoma cells.Mitochondrial Flashes: Elemental Signaling Events in Eukaryotic Cells.Reactive Oxygen Species and Oxidative Stress in Obesity-Recent Findings and Empirical Approaches.Mitochondrial flashes: new insights into mitochondrial ROS signalling and beyond.Mitochondrial flashes: From indicator characterization to in vivo imaging.Deficiency of PHB complex impairs respiratory supercomplex formation and activates mitochondrial flashes.

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Mitochondrial superoxide flashes: metabolic biomarkers of skeletal muscle activity and disease

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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Feliciano Protasi

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Gheorghe Salahura

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Lan Wei

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Robert T Dirksen

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Shey-Shing Sheu

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Simona Boncompagni

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Mitochondria: a historical review

Superoxide flashes in mouse skeletal muscle are produced by discrete arrays of active mitochondria operating coherently

Free radicals in the physiological control of cell function

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

The pathophysiology of mitochondrial cell death

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

Mitochondria are linked to calcium stores in striated muscle by developmentally regulated tethering structures.

Ca2+ release dynamics in parotid and pancreatic exocrine acinar cells evoked by spatially limited flash photolysis.

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