Fusion-activated Ca2+ entry via vesicular P2X4 receptors promotes fusion pore opening and exocytotic content release in pneumocytes
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Primitive ATP-activated P2X receptors: discovery, function and pharmacologyTwo-pore channels at the intersection of endolysosomal membrane trafficImaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorinAnnexins as Overlooked Regulators of Membrane Trafficking in Plant CellsP2X4 forms functional ATP-activated cation channels on lysosomal membranes regulated by luminal pH.Human decidua-derived mesenchymal stem cells differentiate into functional alveolar type II-like cells that synthesize and secrete pulmonary surfactant complexes.Pulmonary surfactant preserves viability of alveolar type II cells exposed to polymyxin B in vitroActin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles.Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion.Interfacial stress affects rat alveolar type II cell signaling and gene expression.P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate NucleusThe trafficking and targeting of P2X receptors.Optical control of trimeric P2X receptors and acid-sensing ion channelsA new role for P2X4 receptors as modulators of lung surfactant secretion.Unproductive exocytosis.Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V-ATPase generated voltage gradient as the driving force.Purinergic signalling links mechanical breath profile and alveolar mechanics with the pro-inflammatory innate immune response causing ventilation-induced lung injury.The P2X4 purinergic receptor impacts liver regeneration after partial hepatectomy in mice through the regulation of biliary homeostasis.A haplotype spanning P2X7R, P2X4R and CAMKK2 may mark susceptibility to pulmonary non-tuberculous mycobacterial disease.The role of myosin 1c and myosin 1b in surfactant exocytosis.Vesicular control of fusion pore expansionSurfactant secretion in LRRK2 knock-out rats: changes in lamellar body morphology and rate of exocytosis.Calcium-dependent regulation of Rab activation and vesicle fusion by an intracellular P2X ion channel.Vesicular calcium channels as regulators of the exocytotic post-fusion phase.Synaptotagmin-7 links fusion-activated Ca²⁺ entry and fusion pore dilation.ATP is stored in lamellar bodies to activate vesicular P2X4 in an autocrine fashion upon exocytosis.A role for P2X4 receptors in lysosome function.Excessive Extracellular ATP Desensitizes P2Y2 and P2X4 ATP Receptors Provoking Surfactant Impairment Ending in Ventilation-Induced Lung Injury.Pore forming channels as a drug delivery system for photodynamic therapy in cancer associated with nanoscintillators.
P2860
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P2860
Fusion-activated Ca2+ entry via vesicular P2X4 receptors promotes fusion pore opening and exocytotic content release in pneumocytes
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Fusion-activated Ca2+ entry vi ...... content release in pneumocytes
@ast
Fusion-activated Ca2+ entry vi ...... content release in pneumocytes
@en
type
label
Fusion-activated Ca2+ entry vi ...... content release in pneumocytes
@ast
Fusion-activated Ca2+ entry vi ...... content release in pneumocytes
@en
prefLabel
Fusion-activated Ca2+ entry vi ...... content release in pneumocytes
@ast
Fusion-activated Ca2+ entry vi ...... content release in pneumocytes
@en
P2093
P2860
P356
P1476
Fusion-activated Ca2+ entry vi ...... content release in pneumocytes
@en
P2093
Edward Felder
Manfred Frick
Melanie Timmler
Norbert Mair
Oliver H Wittekindt
Paul Dietl
Pika Miklavc
P2860
P304
14503-14508
P356
10.1073/PNAS.1101039108
P407
P577
2011-08-15T00:00:00Z