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Influence of exposure history on the immunology and development of resistance to human Schistosomiasis mansoniA systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoniIL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasisParasitic worms and inflammatory diseasesMicro-geographical variation in exposure to Schistosoma mansoni and malaria, and exacerbation of splenomegaly in Kenyan school-aged childrenPolarized Th2 like cells, in the absence of Th0 cells, are responsible for lymphocyte produced IL-4 in high IgE-producer schistosomiasis patientsExposure to malaria affects the regression of hepatosplenomegaly after treatment for Schistosoma mansoni infection in Kenyan childrenIdentification of Schistosoma mansoni gender-associated gene transcripts by cDNA microarray profilingChanges in IgE- and antigen-dependent histamine-release in peripheral blood of Schistosoma mansoni-infected Ugandan fishermen after treatment with praziquantelCharacterization of the Schistosoma transcriptome opens up the world of helminth genomicsComparative study of transcriptome profiles of mechanical- and skin-transformed Schistosoma mansoni schistosomulaEpidemiology and interactions of Human Immunodeficiency Virus – 1 and Schistosoma mansoni in sub-Saharan AfricaAnalysis of complex patterns of human exposure and immunity to Schistosomiasis mansoni: the influence of age, sex, ethnicity and IgEParamyosin is a major target of the human IgA response against Schistosoma japonicum.Identification of the Schistosoma japonicum 22.6-kDa antigen as a major target of the human IgE response: similarity of IgE-binding epitopes to allergen peptides.IPSE/alpha-1, a major secretory glycoprotein antigen from schistosome eggs, expresses the Lewis X motif on core-difucosylated N-glycans.Age-adjusted Plasmodium falciparum antibody levels in school-aged children are a stable marker of microgeographical variations in exposure to Plasmodium infection.Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trialPosttreatment changes in cytokines induced by Schistosoma mansoni egg and worm antigens: dissociation of immunity- and morbidity-associated type 2 responses.Immunity after treatment of human schistosomiasis: association between cellular responses and resistance to reinfection.Human IgE responses to different splice variants of Schistosoma mansoni tropomyosin: associations with immunity.Health implications of chronic hepatosplenomegaly in Kenyan school-aged children chronically exposed to malarial infections and Schistosoma mansoni.Immune modulation by Schistosoma mansoni antigens in NOD mice: effects on both innate and adaptive immune systems.Immunology of hepatosplenic schistosomiasis mansoni: a human perspective.Association of schistosomiasis with false-positive HIV test results in an African adolescent population.Development of antibody isotype responses to Schistosoma mansoni in an immunologically naive immigrant population: influence of infection duration, infection intensity, and host age.Effect of praziquantel treatment during pregnancy on cytokine responses to schistosome antigens: results of a randomized, placebo-controlled trial.Aflatoxin exposure is inversely associated with IGF1 and IGFBP3 levels in vitro and in Kenyan schoolchildrenDehydroepiandrosterone sulfate treatment of mice modulates infection with Schistosoma mansoni.Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial.Chronic hepatosplenomegaly in African school children: a common but neglected morbidity associated with schistosomiasis and malaria.The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses.Suppression of basophil histamine release and other IgE-dependent responses in childhood Schistosoma mansoni/hookworm coinfection.Use of humanised rat basophilic leukaemia cell line RS-ATL8 for the assessment of allergenicity of Schistosoma mansoni proteins.Differential anti-glycan antibody responses in Schistosoma mansoni-infected children and adults studied by shotgun glycan microarray.Human Schistosoma haematobium antifecundity immunity is dependent on transmission intensity and associated with immunoglobulin G1 to worm-derived antigensFactors affecting human IgE and IgG responses to allergen-like Schistosoma mansoni antigens: Molecular structure and patterns of in vivo exposure.Eosinophil activity in Schistosoma mansoni infections in vivo and in vitro in relation to plasma cytokine profile pre- and posttreatment with praziquantel.Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils.Co-infection with Schistosoma mansoni and Human Immunodeficiency Virus-1 (HIV-1) among residents of fishing villages of north-western Tanzania.
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description
hulumtues
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onderzoeker
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researcher
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հետազոտող
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name
David Dunne
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David W Dunne
@en
David W Dunne
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David W Dunne
@nl
David W Dunne
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type
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David Dunne
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David W Dunne
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David W Dunne
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David W Dunne
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David W Dunne
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D W Dunne
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David Dunne
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David W Dunne
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David W Dunne
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David W Dunne
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David W Dunne
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P21
P31
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0000-0002-8940-9886