Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression. - Test2 - elhamkhani - TriplyDB

Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression.

Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression.

http://www.wikidata.org/entity/Q30525522

about

Inhibitory signalling to the Arp2/3 complex steers cell migration Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma Rho GTPase signalling in cell migration The melanocyte lineage in development and disease Pseudopod growth and evolution during cell movement is controlled through SCAR/WAVE dephosphorylation.Reconciling diverse mammalian pigmentation patterns with a fundamental mathematical model Regulation and function of P-Rex family Rac-GEFs Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo.Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation.Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton Forces generated by cell intercalation tow epidermal sheets in mammalian tissue morphogenesis.The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.Ex vivo culture of mouse embryonic skin and live-imaging of melanoblast migration Angiotropism, pericytic mimicry and extravascular migratory metastasis in melanoma: an alternative to intravascular cancer dissemination.Fucci2a: a bicistronic cell cycle reporter that allows Cre mediated tissue specific expression in mice.Identification of metastasis-suppressive microRNAs in primary melanoma Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.Targeting of Rac GTPases blocks the spread of intact human breast cancer.Activated mutant NRas(Q61K) drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism.The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation Monitoring extra-vascular migratory metastasis (EVMM) of migrating cancer cells using an in vitro co-culture system.p21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear.Emerging molecular targets in melanoma invasion and metastasis.Cellular and molecular mechanisms controlling the migration of melanocytes and melanoma cells.Pharmacological inhibition of actin assembly to target tumor cell motility.The biology of melanocyte and melanocyte stem cell.Hair curvature: a natural dialectic and review.The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues Rho GTPases and cancer.Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin.A reporter mouse model for in vivo tracing and in vitro molecular studies of melanocytic lineage cells and their diseases.Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.Pulsed ultrasound promotes melanoblast migration through upregulation of macrophage colony-stimulating factor/focal adhesion kinase autocrine signaling and paracrine mechanisms.A Rac1-independent role for P-Rex1 in melanoblasts.Could pericytic mimicry represent another type of melanoma cell plasticity with embryonic properties?Suppression of RAC1-driven malignant melanoma by group A PAK inhibitors.Role of region-distinctive expression of Rac1 in regulating fibronectin arrangement during palatal shelf elevation.Melanoblasts on the move: Rac1 sets the pace.

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Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression.

http://www.wikidata.org/entity/Q30525522

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

Rac1 drives melanoblast organi ...... ty and cell-cycle progression.

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Rac1 drives melanoblast organi ...... ty and cell-cycle progression.

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type

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Rac1 drives melanoblast organi ...... ty and cell-cycle progression.

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Rac1 drives melanoblast organi ...... ty and cell-cycle progression.

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Rac1 drives melanoblast organi ...... ty and cell-cycle progression.

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Rac1 drives melanoblast organi ...... ty and cell-cycle progression.

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J.DEVCEL.2011.07.008

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Developmental Cell

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Rac1 drives melanoblast organi ...... ty and cell-cycle progression.

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Ang Li

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Colin R Lindsay

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Douglas Strathdee

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Laura M Machesky

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Lionel Larue

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Richard L Mort

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Scott B Snapper

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Xinzi Yu

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P2860

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

Structure and control of the actin regulatory WAVE complex

Characterization of RAC3, a novel member of the Rho family

rac, a novel ras-related family of proteins that are botulinum toxin substrates

Cell motility through plasma membrane blebbing

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse

An actin-based wave generator organizes cell motility

Characterization of two classes of small molecule inhibitors of Arp2/3 complex

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10.1016/J.DEVCEL.2011.07.008

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4

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Robert H Insall

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2011-09-15T00:00:00Z

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51649390

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21924960

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3464460

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