Tubulin acetyltransferase αTAT1 destabilizes microtubules independently of its acetylation activity. - Test2 - elhamkhani - TriplyDB

Tubulin acetyltransferase αTAT1 destabilizes microtubules independently of its acetylation activity.

Tubulin acetyltransferase αTAT1 destabilizes microtubules independently of its acetylation activity.

http://www.wikidata.org/entity/Q30537332

about

Mice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortion Structure and mechanism of non-histone protein acetyltransferase enzymes Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.αTAT1 is the major α-tubulin acetyltransferase in mice Acetylated tubulin is essential for touch sensation in mice TgATAT-Mediated α-Tubulin Acetylation Is Required for Division of the Protozoan Parasite Toxoplasma gondii A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development.Α-tubulin K40 acetylation is required for contact inhibition of proliferation and cell-substrate adhesion Loss of MEC-17 leads to microtubule instability and axonal degeneration.Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations.Kinesin-13 regulates the quantity and quality of tubulin inside cilia.Effects of αTAT1 and HDAC5 on axonal regeneration in adult neurons.Post-translational modifications of tubulin: pathways to functional diversity of microtubules.Immune synapse: conductor of orchestrated organelle movement.αTAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells A conceptual view at microtubule plus end dynamics in neuronal axons.Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1.Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure The contractile vacuole complex of protists--new cues to function and biogenesis.GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2.Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate α-tubulin acetyltransferase-1 (αTAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress.Posttranslational Modifications of Tubulin and Cilia.Microtubules acquire resistance from mechanical breakage through intralumenal acetylation Role of LPS-elicited signaling in triggering gastric mucosal inflammatory responses to H. pylori: modulatory effect of ghrelin.Inhibition of HDAC6 deacetylase activity increases its binding with microtubules and suppresses microtubule dynamic instability in MCF-7 cells.Acetylation as a mechanism that regulates axonal regeneration.Tubulin Post-Translational Modifications and Microtubule Dynamics.Structural and functional features of lysine acetylation of plant and animal tubulins.α-Tubulin Acetylation Restricts Axon Overbranching by Dampening Microtubule Plus-End Dynamics in Neurons.Tubulin acetylation: A novel functional avenue for CDYL in sperm.Spatial pattern formation in microtubule post-translational modifications and the tight localization of motor-driven cargo.Helicobacter pylori-induced changes in microtubule dynamics conferred by α-tubulin phosphorylation on Ser/Tyr mediate gastric mucosal secretion of matrix metalloproteinase-9 (MMP-9) and its modulation by ghrelin.α-Tubulin Acetyltransferase Is a Novel Target Mediating Neurite Growth Inhibitory Effects of Chondroitin Sulfate Proteoglycans and Myelin-Associated Glycoprotein.TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth.

P2860

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P2860

Tubulin acetyltransferase αTAT1 destabilizes microtubules independently of its acetylation activity.

http://www.wikidata.org/entity/Q30537332

description

2012 nî lūn-bûn

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2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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Tubulin acetyltransferase αTAT ...... y of its acetylation activity.

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Tubulin acetyltransferase αTAT ...... y of its acetylation activity.

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Tubulin acetyltransferase αTAT ...... y of its acetylation activity.

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Tubulin acetyltransferase αTAT ...... y of its acetylation activity.

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Tubulin acetyltransferase αTAT ...... y of its acetylation activity.

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Tubulin acetyltransferase αTAT ...... y of its acetylation activity.

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Molecular and Cellular Biology

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Tubulin acetyltransferase αTAT ...... y of its acetylation activity.

@en

P2093

Annapaola Andolfo

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Concepcion Martinez

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Daniel Bilbao-Cortes

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Emerald Perlas

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Karol Fiedorczuk

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Nereo Kalebic

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Paul A Heppenstall

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Philip Hublitz

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P2860

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.

HDAC6 is a microtubule-associated deacetylase

MEC-17 is an alpha-tubulin acetyltransferase

Structure of the α-tubulin acetyltransferase, αTAT1, and implications for tubulin-specific acetylation

Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt

Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin

HEF1-dependent Aurora A activation induces disassembly of the primary cilium

Catalytic mechanism of a MYST family histone acetyltransferase

Mechanisms of P/CAF auto-acetylation

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1114-1123

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10.1128/MCB.01044-12

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6

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33

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2012-12-28T00:00:00Z

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234012078

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23275437

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3592022

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