The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing
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Regulation of mammalian transcription and splicing by Nuclear RNAiBiogenesis, turnover, and mode of action of plant microRNAsSingle molecule fluorescence approaches shed light on intracellular RNAsThe panorama of miRNA-mediated mechanisms in mammalian cellsVisualizing lipid-formulated siRNA release from endosomes and target gene knockdown.A new role for the GARP complex in microRNA-mediated gene regulationMembrane-association of mRNA decapping factors is independent of stress in budding yeast.RNAi factors are present and active in human cell nucleiSynaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic β-cellsRNA-mediated degradation of microRNAs: A widespread viral strategy?Trans-acting small interfering RNA4: key to nutraceutical synthesis in grape development?Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paperExosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ERVisualization of self-delivering hydrophobically modified siRNA cellular internalization.Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma.Dephosphorylation of tyrosine 393 in argonaute 2 by protein tyrosine phosphatase 1B regulates gene silencing in oncogenic RAS-induced senescence.Multifunctional roles for the protein translocation machinery in RNA anchoring to the endoplasmic reticulum.Traffic into silence: endomembranes and post-transcriptional RNA silencing.Mature miRNAs form secondary structure, which suggests their function beyond RISC.Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading.dsRNA binding protein PACT/RAX in gene silencing, development and diseases.Identification of AGO3-associated miRNAs and computational prediction of their targets in the green alga Chlamydomonas reinhardtii.Guanabenz (Wytensin™) selectively enhances uptake and efficacy of hydrophobically modified siRNAs.Diversity and selectivity in mRNA translation on the endoplasmic reticulummiRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets.Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors.The Whereabouts of microRNA Actions: Cytoplasm and Beyond.Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.Poly-Cross-Linked PEI Through Aromatically Conjugated Imine Linkages as a New Class of pH-Responsive Nucleic Acids Packing Cationic Polymers.TLR9-Targeted SiRNA Delivery In VivoPDL1 Regulation by p53 via miR-34Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells.Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling.Destroy and exploit: catalyzed removal of hydroperoxides from the endoplasmic reticulumDextran functionalization enhances nanoparticle-mediated siRNA delivery and silencing.Trip to ER: MicroRNA-mediated translational repression in plants.Timescales and bottlenecks in miRNA-dependent gene regulation.Biogenesis of phased siRNAs on membrane-bound polysomes in Arabidopsis.The conserved SNARE SEC-22 localizes to late endosomes and negatively regulates RNA interference in Caenorhabditis elegans.Differential RISC association of endogenous human microRNAs predicts their inhibitory potential.
P2860
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P2860
The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing
@ast
The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing
@en
type
label
The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing
@ast
The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing
@en
prefLabel
The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing
@ast
The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing
@en
P2093
P2860
P50
P356
P1433
P1476
The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing
@en
P2093
Anja Fritzsche
David V Morrissey
Dominic Trojer
Jan Weiler
Justin Hean
Lukas Stalder
Martin Hintersteiner
Nicole C Meisner-Kober
Pascal Basselet
P2860
P304
P356
10.1038/EMBOJ.2013.52
P407
P577
2013-03-19T00:00:00Z