Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
about
Molecular signaling network motifs provide a mechanistic basis for cellular threshold responsesStable heterogeneity for the production of diffusible factors in cell populationsAdaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety AssessmentPhosphorelays provide tunable signal processing capabilities for the celleEF1A is an S-RNase binding factor in self-incompatible Solanum chacoenseEnzyme Sequestration as a Tuning Point in Controlling Response Dynamics of Signalling NetworksComplete integrability of information processing by biochemical reactionsInput-output relations in biological systems: measurement, information and the Hill equation.Low-Dose Dose-Response for In Vitro Nrf2-ARE Activation in Human HepG2 CellsDigital and analog gene circuits for biotechnology.Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors.The human toxome projectQuantification of pre-mRNA escape rate and synergy in splicing.Determinants of cell-to-cell variability in protein kinase signaling.A model for sigma factor competition in bacterial cellsPhosphate sink containing two-component signaling systems as tunable threshold devices.Logical-continuous modelling of post-translationally regulated bistability of curli fiber expression in Escherichia coli.Multi-objective optimization framework to obtain model-based guidelines for tuning biological synthetic devices: an adaptive network case.Nonlinear Dynamics in Gene Regulation Promote Robustness and Evolvability of Gene Expression LevelsChemical Reaction Network Theory elucidates sources of multistability in interferon signaling.Computational modeling of the cell-autonomous mammalian circadian oscillator.SiGNet: A signaling network data simulator to enable signaling network inference.Noise in multiple sclerosis: unwanted and necessary.Identifying ultrasensitive HGF dose-response functions in a 3D mammalian system for synthetic morphogenesis.A PGC-1α-Mediated Transcriptional Network Maintains Mitochondrial Redox and Bioenergetic Homeostasis against Doxorubicin-Induced Toxicity in Human Cardiomyocytes: Implementation of TT21C.Linear-No-Threshold Default Assumptions are Unwarranted for Cytotoxic Endpoints Independently Triggered by Ultrasensitive Molecular Switches.Linear-No-Threshold Default Assumptions for Noncancer and Nongenotoxic Cancer Risks: A Mathematical and Biological Critique.Controlling long-term signaling: receptor dynamics determine attenuation and refractory behavior of the TGF-β pathway.Pathway Based Toxicology and Fit-for-Purpose Assays.A Synonymous Mutation Upstream of the Gene Encoding a Weak-Link Enzyme Causes an Ultrasensitive Response in Growth Rate.The role of the hypothalamic-pituitary-adrenal axis in modulating seasonal changes in immunity.Rapid engineering of versatile molecular logic gates using heterologous genetic transcriptional modules.Microtiter plate tests for segregation of bioluminescent bacteria.Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations.Impact of upstream and downstream constraints on a signaling module's ultrasensitivity.Interplay of microRNA and epigenetic regulation in the human regulatory network.Engineering modular and tunable genetic amplifiers for scaling transcriptional signals in cascaded gene networks.BioJazz: in silico evolution of cellular networks with unbounded complexity using rule-based modeling.A self-regulating biomolecular comparator for processing oscillatory signalsUsing the population-shift mechanism to rationally introduce "Hill-type" cooperativity into a normally non-cooperative receptor.
P2860
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P2860
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
description
2013 nî lūn-bûn
@nan
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
@ast
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
@en
type
label
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
@ast
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
@en
prefLabel
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
@ast
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
@en
P2860
P356
P1433
P1476
Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.
@en
P2093
Qiang Zhang
P2860
P304
P356
10.1098/RSOB.130031
P577
2013-04-24T00:00:00Z