Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation.
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Nucleocytoplasmic transport of Alp7/TACC organizes spatiotemporal microtubule formation in fission yeastSpatiotemporal Regulation of Nuclear Transport Machinery and Microtubule OrganizationMAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formationAurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle AssemblyThe spindle pole bodies facilitate nuclear envelope division during closed mitosis in fission yeastNucleocytoplasmic shuttling of the TACC protein Mia1p/Alp7p is required for remodeling of microtubule arrays during the cell cycleAlp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism.Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase BTACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylationThe fission yeast transforming acidic coiled coil-related protein Mia1p/Alp7p is required for formation and maintenance of persistent microtubule-organizing centers at the nuclear envelope.Fission yeast Alp14 is a dose-dependent plus end-tracking microtubule polymeraseAlp7/TACC recruits kinesin-8-PP1 to the Ndc80 kinetochore protein for timely mitotic progression and chromosome movement.CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly.The Xenopus TACC homologue, maskin, functions in mitotic spindle assemblyMini spindles, the XMAP215 homologue, suppresses pausing of interphase microtubules in Drosophila.Csi1p recruits alp7p/TACC to the spindle pole bodies for bipolar spindle formation.Sos7, an essential component of the conserved Schizosaccharomyces pombe Ndc80-MIND-Spc7 complex, identifies a new family of fungal kinetochore proteinsThe microtubule lattice and plus-end association of Drosophila Mini spindles is spatially regulated to fine-tune microtubule dynamics.Condensin HEAT subunits required for DNA repair, kinetochore/centromere function and ploidy maintenance in fission yeastCdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation.Fission yeast cytoskeletons and cell polarity factors: connecting at the cortex.The internal loop of fission yeast Ndc80 binds Alp7/TACC-Alp14/TOG and ensures proper chromosome attachment.Retrograde traffic from the Golgi to the endoplasmic reticulum.Fission yeast kinesin-8 Klp5 and Klp6 are interdependent for mitotic nuclear retention and required for proper microtubule dynamics.Space shuttling in the cell: nucleocytoplasmic transport and microtubule organization during the cell cycle.Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP.Shaping microtubules into diverse patterns: molecular connections for setting up both ends.Differentiating the roles of microtubule-associated proteins at meiotic kinetochores during chromosome segregation.The role of TACC3 in mitotic spindle organization.An unconventional interaction between Dis1/TOG and Mal3/EB1 in fission yeast promotes the fidelity of chromosome segregation.The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner.Targeting Alp7/TACC to the spindle pole body is essential for mitotic spindle assembly in fission yeast.Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis.Ndc80 Loop as a protein-protein interaction motif.Microtubules and Alp7-Alp14 (TACC-TOG) reposition chromosomes before meiotic segregation.A microtubule polymerase cooperates with the kinesin-6 motor and a microtubule cross-linker to promote bipolar spindle assembly in the absence of kinesin-5 and kinesin-14 in fission yeast.Disruption of Tacc3 function leads to in vivo tumor regression.Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore.The microtubule polymerase Stu2 promotes oligomerization of the γ-TuSC for cytoplasmic microtubule nucleation
P2860
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P2860
Interdependency of fission yeast Alp14/TOG and coiled coil protein Alp7 in microtubule localization and bipolar spindle formation.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Interdependency of fission yea ...... and bipolar spindle formation.
@ast
Interdependency of fission yea ...... and bipolar spindle formation.
@en
type
label
Interdependency of fission yea ...... and bipolar spindle formation.
@ast
Interdependency of fission yea ...... and bipolar spindle formation.
@en
prefLabel
Interdependency of fission yea ...... and bipolar spindle formation.
@ast
Interdependency of fission yea ...... and bipolar spindle formation.
@en
P2093
P2860
P356
P1476
Interdependency of fission yea ...... and bipolar spindle formation.
@en
P2093
Leah Vardy
Masamitsu Sato
Miguel Angel Garcia
Nirada Koonrugsa
Takashi Toda
P2860
P304
P356
10.1091/MBC.E03-11-0837
P577
2004-01-23T00:00:00Z