Identification of compounds with binding affinity to proteins via magnetization transfer from bulk water.
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"Rules of Engagement" of Protein-Glycoconjugate Interactions: A Molecular View Achievable by using NMR Spectroscopy and Molecular ModelingProtein-carbohydrate interactions studied by NMR: from molecular recognition to drug designOptimization of the Interligand Overhauser Effect for Fragment Linking: Application to Inhibitor Discovery against Mycobacterium tuberculosis Pantothenate SynthetaseStructure of the HIV-1 Frameshift Site RNA Bound to a Small Molecule Inhibitor of Viral ReplicationTargeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α InteractionTargeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B BromodomainIs NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein–Protein Interactions?Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albuminDiscovery of fragment molecules that bind the human peroxiredoxin 5 active siteA kernel for open source drug discovery in tropical diseasesApaf-1 inhibitors protect from unwanted cell death in in vivo models of kidney ischemia and chemotherapy induced ototoxicityNormal tissue radioprotection by amifostine via Warburg-type effectsAccidental interaction between PDZ domains and diclofenac revealed by NMR-assisted virtual screening.NMR approaches in structure-based lead discovery: recent developments and new frontiers for targeting multi-protein complexesAdvances in Nuclear Magnetic Resonance for Drug Discovery.Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.NMR-based analysis of protein-ligand interactions.Biomolecular ligands screening using radiation damping difference WaterLOGSY spectroscopy.Data quality in drug discovery: the role of analytical performance in ligand binding assays.Overview of Probing Protein-Ligand Interactions Using NMR.Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins.Discovery of ligands for Nurr1 by combined use of NMR screening with different isotopic and spin-labeling strategies.Selection and characterization of small molecules that bind the HIV-1 frameshift site RNA.Rapid acquisition of 1H and 19F NMR experiments for direct and competition ligand-based screening.The interaction of La(3+) complexes of DOTA/DTPA glycoconjugates with the RCA(120) lectin: a saturation transfer difference NMR spectroscopic study.WaterLOGSY NMR experiments in conjunction with molecular-dynamics simulations identify immobilized water molecules that bridge peptide mimic MDWNMHAA to anticarbohydrate antibody SYA/J6.An NMR strategy for fragment-based ligand screening utilizing a paramagnetic lanthanide probe.Emerging role of surface plasmon resonance in fragment-based drug discovery.Monomeric α-synuclein binds Congo Red micelles in a disordered mannerBlue news update: BODIPY-GTP binds to the blue-light receptor YtvA while GTP does not.Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.Fragment-based drug discovery using NMR spectroscopyNovel G-quadruplex stabilizing agents: in-silico approach and dynamics.Interaction of Avibactam with Class B Metallo-β-Lactamases.Development of fragment-based n-FABS NMR screening applied to the membrane enzyme FAAH.Perspectives on NMR in drug discovery: a technique comes of ageDesign and generation of highly diverse fluorinated fragment libraries and their efficient screening with improved (19) F NMR methodology.A three-stage biophysical screening cascade for fragment-based drug discovery.Discovery of novel FabF ligands inspired by platensimycin by integrating structure-based design with diversity-oriented synthetic accessibility.Biofragments: an approach towards predicting protein function using biologically related fragments and its application to Mycobacterium tuberculosis CYP126.
P2860
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P2860
Identification of compounds with binding affinity to proteins via magnetization transfer from bulk water.
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Identification of compounds wi ...... tion transfer from bulk water.
@ast
Identification of compounds wi ...... tion transfer from bulk water.
@en
type
label
Identification of compounds wi ...... tion transfer from bulk water.
@ast
Identification of compounds wi ...... tion transfer from bulk water.
@en
prefLabel
Identification of compounds wi ...... tion transfer from bulk water.
@ast
Identification of compounds wi ...... tion transfer from bulk water.
@en
P2093
P356
P1476
Identification of compounds wi ...... ation transfer from bulk water
@en
P2093
P2888
P356
10.1023/A:1008354229396
P577
2000-09-01T00:00:00Z
P6179
1044151795