Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene.
about
The glucose-6-phosphatase systemFoxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expressionEnzymatic characterization of the pancreatic islet-specific glucose-6-phosphatase-related protein (IGRP)Glucose-6-phosphatase catalytic subunit gene familyCloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genesIdentification and characterisation of a new human glucose-6-phosphatase isoformMoving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose.New lessons in the regulation of glucose metabolism taught by the glucose 6-phosphatase system.Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetesGenetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.A single-nucleotide polymorphism in a methylatable Foxa2 binding site of the G6PC2 promoter is associated with insulin secretion in vivo and increased promoter activity in vitroA genomewide search for type 2 diabetes-susceptibility genes in indigenous Australians.Differential regulation of islet-specific glucose-6-phosphatase catalytic subunit-related protein gene transcription by Pax-6 and Pdx-1.Effects of G6pc2 deletion on body weight and cholesterol in mice.G6PC2 Modulates Fasting Blood Glucose In Male Mice in Response to StressDifferential role of hepatocyte nuclear factor-1 in the regulation of glucose-6-phosphatase catalytic subunit gene transcription by cAMP in liver- and kidney-derived cell lines.Upstream stimulatory factor (USF) and neurogenic differentiation/beta-cell E box transactivator 2 (NeuroD/BETA2) contribute to islet-specific glucose-6-phosphatase catalytic-subunit-related protein (IGRP) gene expression.Selective tonic inhibition of G-6-Pase catalytic subunit, but not G-6-P transporter, gene expression by insulin in vivo.Selective stimulation of G-6-Pase catalytic subunit but not G-6-P transporter gene expression by glucagon in vivo and cAMP in situ.Deletion of the gene encoding the ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein (UGRP)/glucose-6-phosphatase catalytic subunit-beta results in lowered plasma cholesterol and elevated glucagon.Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey.
P2860
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P2860
Structure and promoter activity of an islet-specific glucose-6-phosphatase catalytic subunit-related gene.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Structure and promoter activit ...... atalytic subunit-related gene.
@ast
Structure and promoter activit ...... atalytic subunit-related gene.
@en
type
label
Structure and promoter activit ...... atalytic subunit-related gene.
@ast
Structure and promoter activit ...... atalytic subunit-related gene.
@en
prefLabel
Structure and promoter activit ...... atalytic subunit-related gene.
@ast
Structure and promoter activit ...... atalytic subunit-related gene.
@en
P2093
P1433
P1476
Structure and promoter activit ...... atalytic subunit-related gene.
@en
P2093
C A Svitek
C E Mathews
E H Leiter
J C Hutton
J K Goldman
L J Bischof
R M O'Brien
R S Streeper
S C Chapman
P304
P356
10.2337/DIABETES.48.3.543
P407
P577
1999-03-01T00:00:00Z