Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects.

Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects.

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http://www.wikidata.org/entity/Q30655105

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The Fpg/Nei family of DNA glycosylases: substrates, structures, and search for damage The Miscoding Potential of 5-Hydroxycytosine Arises Due to Template Instability in the Replicative Polymerase Active Site Mass spectrometry for the assessment of the occurrence and biological consequences of DNA adducts Mycobacterial MazG safeguards genetic stability via housecleaning of 5-OH-dCTP Synthesis and thermodynamic studies of oligonucleotides containing the two isomers of thymine glycol.Determination of photomodified oligodeoxynucleotides by exonuclease digestion, matrix-assisted laser desorption/ionization and post-source decay mass spectrometry.Characterization of DNA glycosylase activity by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.2'-Deoxycytidine glycols, a missing link in the free radical-mediated oxidation of DNA.Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway.A thermostable endonuclease III homolog from the archaeon Pyrobaculum aerophilum Dehydration, deamination and enzymatic repair of cytosine glycols from oxidized poly(dG-dC) and poly(dI-dC)A base-independent repair mechanism for DNA glycosylase--no discrimination within the active site.Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli A continuous hyperchromicity assay to characterize the kinetics and thermodynamics of DNA lesion recognition and base excision Nonhomologous end joining of complex DNA double-strand breaks with proximal thymine glycol and interplay with base excision repair On the chemical yield of base lesions, strand breaks, and clustered damage generated in plasmid DNA by the direct effect of X rays.Ntg2p, a Saccharomyces cerevisiae DNA N-glycosylase/apurinic or apyrimidinic lyase involved in base excision repair of oxidative DNA damage, interacts with the DNA mismatch repair protein Mlh1p. Identification of a Mlh1p binding motif.Clustered DNA damage, influence on damage excision by XRS5 nuclear extracts and Escherichia coli Nth and Fpg proteins.In vitro DNA synthesis opposite oxazolone and repair of this DNA damage using modified oligonucleotides.Gas-Phase Studies of Formamidopyrimidine Glycosylase (Fpg) Substrates.Fluorescent probes for the analysis of DNA strand scission in base excision repair.The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.Escherichia coli Fpg glycosylase is nonrendundant and required for the rapid global repair of oxidized purine and pyrimidine damage in vivo Formation of isodialuric acid lesion within DNA oligomers via one-electron oxidation of 5-hydroxyuracil: characterization, stability and excision repair Repair of oxidized purines and damaged pyrimidines by E. coli Fpg protein: different roles of proline 2 and lysine 57 residues.Oxidative DNA damage by a common metabolite of carcinogenic nitrofluorene and N-acetylaminofluorene.Oxidative DNA damage by hyperglycemia-related aldehydes and its marked enhancement by hydrogen peroxide.Substrate discrimination by formamidopyrimidine-DNA glycosylase: a mutational analysis.Excision by the human methylpurine DNA N-glycosylase of cyanuric acid, a stable and mutagenic oxidation product of 8-oxo-7,8-dihydroguanine.Dihydrothymine lesion in X-irradiated DNA: characterization at the molecular level and detection in cells.Synthesis of a convenient thymidine glycol phosphoramidite monomer and its site-specific incorporation into DNA fragments.

P2860

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P2860

Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects.

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http://www.wikidata.org/entity/Q30655105

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