Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice.
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Pangaea and the Out-of-Africa Model of Varicella-Zoster Virus Evolution and PhylogeographyCase report: occupationally related recurrent varicella (chickenpox) in a hospital nurse.Sequencing of 21 varicella-zoster virus genomes reveals two novel genotypes and evidence of recombinationThe insulin degrading enzyme binding domain of varicella-zoster virus (VZV) glycoprotein E is important for cell-to-cell spread and VZV infectivity, while a glycoprotein I binding domain is essential for infection.Functions of the unique N-terminal region of glycoprotein E in the pathogenesis of varicella-zoster virus infectionInsulin degrading enzyme induces a conformational change in varicella-zoster virus gE, and enhances virus infectivity and stabilityMolecular mechanisms of varicella zoster virus pathogenesis.Varicella-Zoster virus pathogenesis and immunobiology: new concepts emerging from investigations with the SCIDhu mouse model.Mutational analysis of the repeated open reading frames, ORFs 63 and 70 and ORFs 64 and 69, of varicella-zoster virus.A proposal for a common nomenclature for viral clades that form the species varicella-zoster virus: summary of VZV Nomenclature Meeting 2008, Barts and the London School of Medicine and Dentistry, 24-25 July 2008.Phylogenetic analysis of varicella-zoster virus: evidence of intercontinental spread of genotypes and recombinationPhosphorylation by the varicella-zoster virus ORF47 protein serine kinase determines whether endocytosed viral gE traffics to the trans-Golgi network or recycles to the cell membrane.Complete DNA sequence analyses of the first two varicella-zoster virus glycoprotein E (D150N) mutant viruses found in North America: evolution of genotypes with an accelerated cell spread phenotype.Mutational analysis of open reading frames 62 and 71, encoding the varicella-zoster virus immediate-early transactivating protein, IE62, and effects on replication in vitro and in skin xenografts in the SCID-hu mouse in vivo.Essential functions of the unique N-terminal region of the varicella-zoster virus glycoprotein E ectodomain in viral replication and in the pathogenesis of skin infectionGlobal identification of three major genotypes of varicella-zoster virus: longitudinal clustering and strategies for genotyping.The amino terminus of varicella-zoster virus (VZV) glycoprotein E is required for binding to insulin-degrading enzyme, a VZV receptor.Cellular and viral factors regulate the varicella-zoster virus gE promoter during viral replication.Novel varicella-zoster virus glycoprotein E gene mutations associated with genotypes A and DDefensive Perimeter in the Central Nervous System: Predominance of Astrocytes and Astrogliosis during Recovery from Varicella-Zoster Virus EncephalitisBioinformatics of varicella-zoster virus: single nucleotide polymorphisms define clades and attenuated vaccine genotypes.Deletion of the first cysteine-rich region of the varicella-zoster virus glycoprotein E ectodomain abolishes the gE and gI interaction and differentially affects cell-cell spread and viral entry.Regulation of the ORF61 promoter and ORF61 functions in varicella-zoster virus replication and pathogenesisNew variant of varicella-zoster virus.Differential requirement for cell fusion and virion formation in the pathogenesis of varicella-zoster virus infection in skin and T cells.Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivo.Functions of the ORF9-to-ORF12 gene cluster in varicella-zoster virus replication and in the pathogenesis of skin infectionPhenotypic and genetic characterization of varicella-zoster virus mutants resistant to acyclovir, brivudine and/or foscarnet.Varicella-zoster Virus gB and gE coexpression, but not gB or gE alone, leads to abundant fusion and syncytium formation equivalent to those from gH and gL coexpression.Promoter sequences of varicella-zoster virus glycoprotein I targeted by cellular transactivating factors Sp1 and USF determine virulence in skin and T cells in SCIDhu mice in vivo.Glycoprotein I of varicella-zoster virus is required for viral replication in skin and T cells.In vitro replication of varicella-zoster virus in human retinal pigment epithelial cellsMutagenesis of varicella-zoster virus glycoprotein B: putative fusion loop residues are essential for viral replication, and the furin cleavage motif contributes to pathogenesis in skin tissue in vivo.Egress of light particles among filopodia on the surface of Varicella-Zoster virus-infected cells.Targeted Genome Sequencing Reveals Varicella-Zoster Virus Open Reading Frame 12 Deletion.The varicella-zoster virus (VZV) ORF9 protein interacts with the IE62 major VZV transactivator.Incorporation of three endocytosed varicella-zoster virus glycoproteins, gE, gH, and gB, into the virion envelopeEnumeration of an extremely high particle-to-PFU ratio for Varicella-zoster virus.Replication of varicella-zoster virus in human skin organ cultureAutophagy and the effects of its inhibition on varicella-zoster virus glycoprotein biosynthesis and infectivity.
P2860
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P2860
Varicella-zoster virus gE escape mutant VZV-MSP exhibits an accelerated cell-to-cell spread phenotype in both infected cell cultures and SCID-hu mice.
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2000 nî lūn-bûn
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2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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name
Varicella-zoster virus gE esca ...... ell cultures and SCID-hu mice.
@ast
Varicella-zoster virus gE esca ...... ell cultures and SCID-hu mice.
@en
type
label
Varicella-zoster virus gE esca ...... ell cultures and SCID-hu mice.
@ast
Varicella-zoster virus gE esca ...... ell cultures and SCID-hu mice.
@en
prefLabel
Varicella-zoster virus gE esca ...... ell cultures and SCID-hu mice.
@ast
Varicella-zoster virus gE esca ...... ell cultures and SCID-hu mice.
@en
P2093
P356
P1433
P1476
Varicella-zoster virus gE esca ...... cell cultures and SCID-hu mice
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P2093
C C Hatfield
J A Padilla
J F Moffat
R A Santos
W T Ruyechan
P304
P356
10.1006/VIRO.2000.0507
P407
P577
2000-09-01T00:00:00Z