Quantification of frequent-hitter behavior based on historical high-throughput screening data.
about
Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?Privileged Structures Revisited.The impact of data integrity on decision making in early lead discovery.PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS.Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.Non-stoichiometric inhibition in integrated lead finding - a literature review.Phantom PAINS: Problems with the Utility of Alerts for Pan-Assay INterference CompoundS.Beyond PAINs: Chemotype Sensitivity of Protein Methyltransferases in Screens.A Generic Platform for Cellular Screening Against Ubiquitin Ligases.Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017-Utility and Limitations.Biology must develop herd immunity against bad-actor molecules.
P2860
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P2860
Quantification of frequent-hitter behavior based on historical high-throughput screening data.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Quantification of frequent-hit ...... igh-throughput screening data.
@ast
Quantification of frequent-hit ...... igh-throughput screening data.
@en
type
label
Quantification of frequent-hit ...... igh-throughput screening data.
@ast
Quantification of frequent-hit ...... igh-throughput screening data.
@en
prefLabel
Quantification of frequent-hit ...... igh-throughput screening data.
@ast
Quantification of frequent-hit ...... igh-throughput screening data.
@en
P2860
P356
P1476
Quantification of frequent-hit ...... igh-throughput screening data.
@en
P2093
J Willem M Nissink
Sam Blackburn
P2860
P304
P356
10.4155/FMC.14.72
P577
2014-06-01T00:00:00Z