Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells.
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Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitroA new paradigm for MAPK: structural interactions of hERK1 with mitochondria in HeLa cellsGeneralized substitution of isoencoding codons shortens the duration of papillomavirus L1 protein expression in transiently gene-transfected keratinocytes due to cell differentiationHuman mitochondrial transcription factor A induces a U-turn structure in the light strand promoterAlternative translation initiation augments the human mitochondrial proteomeTraining-induced mitochondrial adaptation: role of peroxisome proliferator-activated receptor γ coactivator-1α, nuclear factor-κB and β-blockadeAssociation of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituentsTranscription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitroRecombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxinRecombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression.Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafnessThe mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures.Effects on mitochondrial transcription of manipulating mTERF protein levels in cultured human HEK293 cells.Core human mitochondrial transcription apparatus is a regulated two-component system in vitro.The mitochondrial transcription factor A functions in mitochondrial base excision repair.Intrauterine growth retardation increases the susceptibility of pigs to high-fat diet-induced mitochondrial dysfunction in skeletal muscle.Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease.A cryptic targeting signal creates a mitochondrial FEN1 isoform with tailed R-Loop binding properties.Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells.A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restrictionOxidative stress during mitochondrial biogenesis compromises mtDNA integrity in growing hearts and induces a global DNA repair response.Mitochondrial retrograde signaling regulates neuronal functionReduced mtDNA copy number increases the sensitivity of tumor cells to chemotherapeutic drugs.CREB-1alpha is recruited to and mediates upregulation of the cytochrome c promoter during enhanced mitochondrial biogenesis accompanying skeletal muscle differentiation.Two-dimensional intact mitochondrial DNA agarose electrophoresis reveals the structural complexity of the mammalian mitochondrial genome.Mitochondrial DNA damage and the aging process: facts and imaginations.The mitochondrial nucleoid: integrating mitochondrial DNA into cellular homeostasisDigital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions.Regulation of mitochondrial genome replication by hypoxia: The role of DNA oxidation in D-loop regionMouse models of oxidative phosphorylation defects: powerful tools to study the pathobiology of mitochondrial diseases.Mitochondrial role in adaptive response to stress conditions in preeclampsia.Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I.Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications.Human mitochondrial transcription factors TFAM and TFB2M work synergistically in promoter melting during transcription initiation.Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.Effects of dietary leucine supplementation on the hepatic mitochondrial biogenesis and energy metabolism in normal birth weight and intrauterine growth-retarded weanling pigletsMitochondrial DNA transcription regulation and nucleoid organization.Mitochondrial transcription: lessons from mouse models.Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesisMitochondrial transcription in mammalian cells.
P2860
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P2860
Transient overexpression of mitochondrial transcription factor A (TFAM) is sufficient to stimulate mitochondrial DNA transcription, but not sufficient to increase mtDNA copy number in cultured cells.
description
2004 nî lūn-bûn
@nan
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Transient overexpression of mi ...... copy number in cultured cells.
@ast
Transient overexpression of mi ...... copy number in cultured cells.
@en
type
label
Transient overexpression of mi ...... copy number in cultured cells.
@ast
Transient overexpression of mi ...... copy number in cultured cells.
@en
prefLabel
Transient overexpression of mi ...... copy number in cultured cells.
@ast
Transient overexpression of mi ...... copy number in cultured cells.
@en
P2093
P2860
P921
P356
P1476
Transient overexpression of mi ...... copy number in cultured cells.
@en
P2093
Heike L Garstka
Julio Montoya
Katharina Maniura-Weber
Rudolf J Wiesner
Steffi Goffart
P2860
P304
P356
10.1093/NAR/GKH921
P407
P577
2004-11-16T00:00:00Z