Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib
about
To wake up cancer stem cells, or to let them sleep, that is the questionQuantitative modeling of chronic myeloid leukemia: insights from radiobiologyFitness conferred by BCR-ABL kinase domain mutations determines the risk of pre-existing resistance in chronic myeloid leukemiaA simple mathematical model based on the cancer stem cell hypothesis suggests kinetic commonalities in solid tumor growthOptimized Treatment Schedules for Chronic Myeloid LeukemiaThe Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues.Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy.A multicellular basis for the origination of blast crisis in chronic myeloid leukemiaThe ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia.Do we need more drugs for chronic myeloid leukemia?Dynamical models of mutated chronic myelogenous leukemia cells for a post-imatinib treatment scenario: Response to dasatinib or nilotinib therapy.Determining the control networks regulating stem cell lineages in colonic crypts.Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis.Robustness of differentiation cascades with symmetric stem cell divisionTracking molecular relapse of chronic myeloid leukemia by measuring Hedgehog signaling status.Nonlinear regulation of commitment to apoptosis by simultaneous inhibition of Bcl-2 and XIAP in leukemia and lymphoma cells.Selection pressure exerted by imatinib therapy leads to disparate outcomes of imatinib discontinuation trials.Therapy of chronic myeloid leukaemia can benefit from the activation of stem cells: simulation studies of different treatment combinations.Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia.Role of STAT3 in Transformation and Drug Resistance in CMLStability of Control Networks in Autonomous Homeostatic Regulation of Stem Cell Lineages.Safety and efficacy of pulsed imatinib with or without G-CSF versus continuous imatinib in chronic phase chronic myeloid leukaemia patients at 5 years follow-up.Determining the role of inflammation in the selection of JAK2 mutant cells in myeloproliferative neoplasms.A pharmacodynamic model of Bcr-Abl signalling in chronic myeloid leukaemia.Long-term treatment effects in chronic myeloid leukemia.The mathematician versus the malignancy.
P2860
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P2860
Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Eradication of chronic myeloid ...... it of adding G-CSF to imatinib
@ast
Eradication of chronic myeloid ...... it of adding G-CSF to imatinib
@en
type
label
Eradication of chronic myeloid ...... it of adding G-CSF to imatinib
@ast
Eradication of chronic myeloid ...... it of adding G-CSF to imatinib
@en
prefLabel
Eradication of chronic myeloid ...... it of adding G-CSF to imatinib
@ast
Eradication of chronic myeloid ...... it of adding G-CSF to imatinib
@en
P2093
P2860
P1476
Eradication of chronic myeloid ...... it of adding G-CSF to imatinib
@en
P2093
Bayard Clarkson
Franziska Michor
Jasmine Foo
Mark W Drummond
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000503
P577
2009-09-11T00:00:00Z