%D8%AA%D9%8A%D9%85_%D9%87%D8%A7%D9%86%D8%AA%D8%AA%DB%8C%D9%85_%D9%87%D8%A7%D9%86%D8%AA%E0%A6%9F%E0%A6%BF%E0%A6%AE_%E0%A6%B9%E0%A6%BE%E0%A6%A8%E0%A7%8D%E0%A6%9FTim_HuntCategory:Tim_HuntTim_HuntR._Timothy_HuntTim_HuntTim_HuntTim_Hunt%D8%AA%DB%8C%D9%85_%D9%87%D8%A7%D9%86%D8%AATim_HuntTim_HuntRichard_Timothy_HuntR._Timothy_HuntTim_Hunt%D4%B9%D5%AB%D5%B4_%D5%80%D5%A1%D5%B6%D5%BFRichard_Timothy_HuntRichard_Timothy_HuntR._Timothy_Hunt%E3%83%86%E3%82%A3%E3%83%A2%E3%82%B7%E3%83%BC%E3%83%BB%E3%83%8F%E3%83%B3%E3%83%88%D0%A2%D0%B8%D0%BC%D0%BE%D1%82%D0%B8_%D0%A5%D0%B0%D0%BD%D1%82%ED%8C%80_%ED%97%8C%ED%8A%B8Tim_HuntRichard_Timothy_HuntTim_HuntTim_HuntTim_HuntTimothy_Hunt%D9%B9%D9%85_%DB%81%D9%86%D9%B9Richard_Timothy_Hunt%D0%A5%D0%B0%D0%BD%D1%82,_%D0%A2%D0%B8%D0%BC%D0%BE%D1%82%D0%B8Tim_HuntTim_HuntTimothy_HuntTim_Hunt%D0%A2%D1%96%D0%BC%D0%BE%D1%82%D1%96_%D0%93%D0%B0%D0%BD%D1%82%D9%B9%D9%85_%DB%81%D9%86%D9%B9Tim_HuntQ309977
about
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Pursuing the impossible: an interview with Tim HuntThe Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6pCDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repairSimian virus 40 large T antigen associates with cyclin A and p33cdk2Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in uteroThe crystal structure of human cyclin BThe structure of CDK4/cyclin D3 has implications for models of CDK activationThe crystal structure of cyclin ACyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage divisionThe small subunit of ribonucleotide reductase is encoded by one of the most abundant translationally regulated maternal RNAs in clam and sea urchin eggs.Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinaseA post-ribosomal supernatant from activated Xenopus eggs that displays post-translationally regulated oscillation of its cdc2+ mitotic kinase activityThe A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs.Double-stranded DNA induces the phosphorylation of several proteins including the 90 000 mol. wt. heat-shock protein in animal cell extractsThe use of single-stranded DNA and RNase H to promote quantitative 'hybrid arrest of translation' of mRNA/DNA hybrids in reticulocyte lysate cell-free translationsMaternal mRNA from clam oocytes can be specifically unmasked in vitro by antisense RNA complementary to the 3'-untranslated region.Messenger RNA for the coat protein of tobacco mosaic virus.Double-stranded poliovirus RNA inhibits initiation of protein synthesis by reticulocyte lysates.Initiation of protein synthesis: evidence for messenger RNA-independent binding of methionyl-transfer RNA to the 40 S ribosomal subunit.Inhibition of protein synthesis by glutathione disulfide in the presence of glutathione.Phosphorylation of initiation factor elF-2 and the control of reticulocyte protein synthesis.Control of haemoglobin synthesis: distribution of ribosomes on the messenger RNA for alpha and beta chains.Plasmid cDNA-directed protein synthesis in a coupled eukaryotic in vitro transcription-translation system.The use of affinity chromatography on 2'5' ADP-sepharose reveals a requirement for NADPH, thioredoxin and thioredoxin reductase for the maintenance of high protein synthesis activity in rabbit reticulocyte lysates.Selective translation of mRNA controls the pattern of protein synthesis during early development of the surf clam, Spisula solidissima.Cyclin synthesis, modification and destruction during meiotic maturation of the starfish oocyte.Cyclin A and the retinoblastoma gene product complex with a common transcription factor.Cyclin is a component of maturation-promoting factor from Xenopus.Cyclin A recruits p33cdk2 to the cellular transcription factor DRTF1.Differential accumulation of ribonucleotide reductase subunits in clam oocytes: the large subunit is stored as a polypeptide, the small subunit as untranslated mRNA.The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryoXenopus oocyte maturation does not require new cyclin synthesis.On the synthesis and destruction of A- and B-type cyclins during oogenesis and meiotic maturation in Xenopus laevis.Cyclins and their partners: from a simple idea to complicated reality.Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits.The role of cyclin synthesis, modification and destruction in the control of cell division.Maturation promoting factor, cyclin and the control of M-phase.Cytoplasmic anchoring proteins and the control of nuclear localization.The use of hexose phosphates to support protein synthesis and generate [gamma-32P]ATP in reticulocyte lysates.
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description
Biochemist; Nobel laureate
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Brits biochemicus
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biochemik angielski, noblista z medycyny
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biochimico britannico
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britischer Biochemiker
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britisk biokjemiker, nobelprisvinner
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chimiste britannique
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প্রাণরসায়নবিদ, নোবেল বিজয়ী।
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Tim Hunt
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Tim Hunt
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Richard Timothy Hunt
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