A protein kinase associated with apoptosis and tumor suppression: structure, activity, and discovery of peptide substrates.
about
Ca2+-dependent phosphorylation of syntaxin-1A by the death-associated protein (DAP) kinase regulates its interaction with Munc18Hypermethylation of p16 and DAPK promoter gene regions in patients with non-invasive urinary bladder cancerDeath Associated Protein Kinase 1 (DAPK1): A Regulator of Apoptosis and AutophagyStructural insight into nucleotide recognition by human death-associated protein kinaseHomodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporterDAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in strokeFluorescence linked enzyme chemoproteomic strategy for discovery of a potent and selective DAPK1 and ZIPK inhibitor.Kinase peptide specificity: improved determination and relevance to protein phosphorylationA single pair of acidic residues in the kinase major groove mediates strong substrate preference for P-2 or P-5 arginine in the AGC, CAMK, and STE kinase families.A novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. phosphorylation at SER269 in vivo is linked to inactivation of p53 function.Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers.Site-directed mutagenesis of the glycine-rich loop of death associated protein kinase (DAPK) identifies it as a key structure for catalytic activity.Protein kinase involved in lung injury susceptibility: evidence from enzyme isoform genetic knockout and in vivo inhibitor treatment.Death-associated protein kinase phosphorylates mammalian ribosomal protein S6 and reduces protein synthesisAssociation between promoter methylation of DAPK gene and HNSCC: A meta-analysis.Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct SitesIdentification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death.Structural and functional diversity in the activity and regulation of DAPK-related protein kinases.DAPK and cytoskeleton-associated functions.The DAPK family: a structure-function analysis.The DAP-kinase interactome.A high throughput proteomics screen identifies novel substrates of death-associated protein kinase.The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members.Identification and characterization of a small-molecule inhibitor of death-associated protein kinase 1.Analysis of promoter hypermethylation of death-associated protein kinase and p16 tumor suppressor genes in actinic keratoses and squamous cell carcinomas of the skin.Domain analysis of a groundnut calcium-dependent protein kinase: nuclear localization sequence in the junction domain is coupled with nonconsensus calcium binding domains.Restoration of DAP Kinase Tumor Suppressor Function: A Therapeutic Strategy to Selectively Induce Apoptosis in Cancer Cells Using Immunokinase Fusion Proteins.
P2860
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P2860
A protein kinase associated with apoptosis and tumor suppression: structure, activity, and discovery of peptide substrates.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A protein kinase associated wi ...... scovery of peptide substrates.
@ast
A protein kinase associated wi ...... scovery of peptide substrates.
@en
type
label
A protein kinase associated wi ...... scovery of peptide substrates.
@ast
A protein kinase associated wi ...... scovery of peptide substrates.
@en
prefLabel
A protein kinase associated wi ...... scovery of peptide substrates.
@ast
A protein kinase associated wi ...... scovery of peptide substrates.
@en
P2093
P2860
P356
P1476
A protein kinase associated wi ...... iscovery of peptide substrates
@en
P2093
P2860
P304
38956-38965
P356
10.1074/JBC.M104273200
P407
P577
2001-08-01T00:00:00Z