Mutant human cells with constitutive activation of NF-kappaB
about
Long-distance effects of insertional mutagenesisRegulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.Mutagenesis by reversible promoter insertion to study the activation of NF-kappaB.Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells.Activation of cAMP-responsive-element-binding protein by PI3 kinase and p38 MAPK is essential for elevated expression of transforming growth factor β2 in cancer cells.Proteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IkappaBalpha.The G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alphaValidation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB.Use of forward genetics to discover novel regulators of NF-kappaB.Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer.CHFR, a potential tumor suppressor, downregulates interleukin-8 through the inhibition of NF-kappaB.Inhibition of nuclear factor kappaB proteins-platinated DNA interactions correlates with cytotoxic effectiveness of the platinum complexes.My life in science, not the restaurant business.
P2860
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P2860
Mutant human cells with constitutive activation of NF-kappaB
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mutant human cells with constitutive activation of NF-kappaB
@ast
Mutant human cells with constitutive activation of NF-kappaB
@en
type
label
Mutant human cells with constitutive activation of NF-kappaB
@ast
Mutant human cells with constitutive activation of NF-kappaB
@en
prefLabel
Mutant human cells with constitutive activation of NF-kappaB
@ast
Mutant human cells with constitutive activation of NF-kappaB
@en
P2093
P2860
P356
P1476
Mutant human cells with constitutive activation of NF-kappaB
@en
P2093
George R Stark
Kalpa Vithalani
Mairead Commane
Nywana Sizemore
Shannon M Swiatkowski
Swati S Sathe
Xiaoxia Li
P2860
P304
P356
10.1073/PNAS.0306812101
P407
P577
2003-12-22T00:00:00Z