MR-Guided Focused Ultrasound SurgeryBlood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index.Ultrasound enhanced drug delivery to the brain and central nervous system.Ultrasound enhanced delivery of molecular imaging and therapeutic agents in Alzheimer's disease mouse modelsIn vitro and in vivo high-intensity focused ultrasound thrombolysisLocal and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonicationsAntitumor effects of combining docetaxel (taxotere) with the antivascular action of ultrasound stimulated microbubblesA Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor.Acute effects of focused ultrasound-induced increases in blood-brain barrier permeability on rat microvascular transcriptome.Emerging non-cancer applications of therapeutic ultrasound.Comparison of analytical and numerical approaches for CT-based aberration correction in transcranial passive acoustic imaging.Opening the Blood-Brain Barrier with MR Imaging-guided Focused Ultrasound: Preclinical Testing on a Trans-Human Skull Porcine Model.Focused Ultrasound-Induced Neurogenesis Requires an Increase in Blood-Brain Barrier Permeability.Experimental demonstration of passive acoustic imaging in the human skull cavity using CT-based aberration corrections.Intracranial applications of magnetic resonance-guided focused ultrasound.Focused ultrasound-mediated drug delivery through the blood-brain barrier.Pulsed focused ultrasound-induced displacements in confined in vitro blood clots.Alzheimer disease in a mouse model: MR imaging-guided focused ultrasound targeted to the hippocampus opens the blood-brain barrier and improves pathologic abnormalities and behavior.High-intensity focused ultrasound sonothrombolysis: the use of perfluorocarbon droplets to achieve clot lysis at reduced acoustic power.Microbubbles and blood-brain barrier opening: a numerical study on acoustic emissions and wall stress predictionsFocused ultrasound delivery of Raman nanoparticles across the blood-brain barrier: potential for targeting experimental brain tumors.Drug delivery across the blood-brain barrier using focused ultrasound.Numerical simulations of clinical focused ultrasound functional neurosurgery.Three-dimensional transcranial ultrasound imaging of microbubble clouds using a sparse hemispherical array.Stimulation of hippocampal neurogenesis by transcranial focused ultrasound and microbubbles in adult mice.Assessing the barriers to image-guided drug delivery.The application of sparse arrays in high frequency transcranial focused ultrasound therapy: a simulation studyDrug delivery to the brain by focused ultrasound induced blood-brain barrier disruption: quantitative evaluation of enhanced permeability of cerebral vasculature using two-photon microscopy.Enhancing drug delivery for boron neutron capture therapy of brain tumors with focused ultrasoundCreating brain lesions with low-intensity focused ultrasound with microbubbles: a rat study at half a megahertz.Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncologyTranscranial passive acoustic mapping with hemispherical sparse arrays using CT-based skull-specific aberration corrections: a simulation studyEnhanced delivery of gold nanoparticles with therapeutic potential into the brain using MRI-guided focused ultrasound.Investigation of standing-wave formation in a human skull for a clinical prototype of a large-aperture, transcranial MR-guided focused ultrasound (MRgFUS) phased array: an experimental and simulation study.Cavitation-based third ventriculostomy using MRI-guided focused ultrasound.The design of a focused ultrasound transducer array for the treatment of stroke: a simulation studyKey factors that affect sonoporation efficiency in in vitro settings: the importance of standing wave in sonoporation.Focused ultrasound for targeted delivery of siRNA and efficient knockdown of Htt expressionNoninvasive and targeted drug delivery to the brain using focused ultrasound.Focused ultrasound delivers targeted immune cells to metastatic brain tumors
P50
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P50
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Finnish physicist
@en
Finnish physicist
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Finnish physicist
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Soome füüsik
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finnischer Physiker
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fisico finlandese
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fisikari finlandiarra
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fizician finlandez
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fizikan finlandez
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físic finlandès
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name
Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
@es
Kullervo Hynynen
@fi
Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
@es
Kullervo Hynynen
@fi
Kullervo Hynynen
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Kullervo Hynynen
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Kullervo Hynynen
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P21
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0000 0000 4860 4795
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1954-01-01T00:00:00Z
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