Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit.
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Molecular determinants of inactivation within the I-II linker of alpha1E (CaV2.3) calcium channels.A specific tryptophan in the I-II linker is a key determinant of beta-subunit binding and modulation in Ca(V)2.3 calcium channelsCoding and noncoding variation of the human calcium-channel beta4-subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia.Evidence for two concentration-dependent processes for beta-subunit effects on alpha1B calcium channelsCritical role for the beta regulatory subunits of Cav channels in T lymphocyte function.The voltage-dependent calcium channel beta subunit contains two stable interacting domainsThe ß subunit of voltage-gated Ca2+ channelsFunctional modularity of the beta-subunit of voltage-gated Ca2+ channels.Transfer of beta subunit regulation from high to low voltage-gated Ca2+ channels.The L-type calcium channel in the heart: the beat goes onVoltage-gated rearrangements associated with differential beta-subunit modulation of the L-type Ca(2+) channel inactivationShort-term regulation of excitation-contraction coupling by the beta1a subunit in adult mouse skeletal muscle.Potentiation of high voltage-activated calcium channels by 4-aminopyridine depends on subunit composition.Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder.Forskolin Regulates L-Type Calcium Channel through Interaction between Actinin 4 and β3 Subunit in Osteoblasts.Up-regulation of Cavβ3 subunit in primary sensory neurons increases voltage-activated Ca2+ channel activity and nociceptive input in neuropathic painRegulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).A central role for ROS in the functional remodelling of L-type Ca2+ channels by hypoxiaOverexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivationDynamic interactions between L-type voltage-sensitive calcium channel Cav1.2 subunits and ahnak in osteoblastic cells.Akt regulates L-type Ca2+ channel activity by modulating Cavalpha1 protein stability.Molecular basis for zinc transporter 1 action as an endogenous inhibitor of L-type calcium channels.Synaptic localization and presynaptic function of calcium channel beta 4-subunits in cultured hippocampal neurons.Folding of active calcium channel beta(1b) -subunit by size-exclusion chromatography and its role on channel function.A mutation in the beta interaction domain of the Ca(2+) channel alpha(1C) subunit reduces the affinity of the (+)-[(3)H]isradipine binding site.A single CaVbeta can reconstitute both trafficking and macroscopic conductance of voltage-dependent calcium channels.Modified sympathetic nerve system activity with overexpression of the voltage-dependent calcium channel beta3 subunit.Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells.Plasma membrane expression of T-type calcium channel alpha(1) subunits is modulated by high voltage-activated auxiliary subunits.Competitive and synergistic interactions of G protein beta(2) and Ca(2+) channel beta(1b) subunits with Ca(v)2.1 channels, revealed by mammalian two-hybrid and fluorescence resonance energy transfer measurements.Cardiac L-type calcium channel beta-subunits expressed in human heart have differential effects on single channel characteristics.A sequence in the carboxy-terminus of the alpha(1C) subunit important for targeting, conductance and open probability of L-type Ca(2+) channels.Modulation of the smooth-muscle L-type Ca2+ channel alpha1 subunit (alpha1C-b) by the beta2a subunit: a peptide which inhibits binding of beta to the I-II linker of alpha1 induces functional uncoupling.Current modulation and membrane targeting of the calcium channel alpha1C subunit are independent functions of the beta subunit.Chronic verapamil treatment remodels ICa,L in mouse ventricle.Use of a purified and functional recombinant calcium-channel beta4 subunit in surface-plasmon resonance studies.Single-channel monitoring of reversible L-type Ca(2+) channel Ca(V)α(1)-Ca(V)β subunit interaction.Morphological transformation induced by activation of the mitogen-activated protein kinase pathway requires suppression of the T-type Ca2+ channel.Stable incorporation versus dynamic exchange of β subunits in a native Ca2+ channel complex.The interaction between the I-II loop and the III-IV loop of Cav2.1 contributes to voltage-dependent inactivation in a beta -dependent manner.
P2860
Q24537411-CAB635ED-4D02-4D85-83AF-65913BDAF2C2Q24537548-727F4B2F-FD0E-4BE1-AC8D-EA3638572FBEQ24540213-89115BA1-80E1-4AC2-9921-9C2CBAA9220CQ28346163-4EDCCA7F-BE0C-4327-B5AD-8F2EA1913E48Q28505265-FB808828-AB84-4295-81AD-5081F11E7D42Q28571202-44423278-967F-49F0-B2DA-7D7851672504Q30155988-5A2A583F-6992-4700-9440-69A443C3A013Q30157978-B5D1F71F-2A52-4178-9157-B3E207A9AD0DQ30437245-CEE4BFAF-CD14-44DB-810E-28AFE2EE540CQ34160273-0B7C5B30-55AF-458F-8710-3C6A9E2CEED0Q34186741-FFCC59F2-D1B5-493E-8F84-99FB605DB7FCQ34352442-B6A7762C-7B36-4093-902A-1177237DAE23Q34573948-D158A5A4-E4AE-45FA-92E8-40FF3D15BEDEQ35553863-3910CBFD-1013-4869-8E7E-7697011ED564Q35611513-F2E89FC3-6EB7-4129-B0ED-B58BE4C5FC4DQ35774149-677B242F-F40F-473D-973A-2F23F89FA140Q36295788-F8FCF1C5-02C7-47EB-9433-70D320B4F164Q36328351-356ECF60-487E-4B6A-86CD-C8D2DF1B89DAQ36412553-9605C9CF-5441-4C73-AFFF-3F68AA56D3F1Q37190325-AE0CC927-6738-45DF-BB2D-6D6F46E7F51EQ37234352-C33C7222-0410-4FA7-99C9-02DF13681970Q37431997-94D3B6DF-A9BD-4DB3-99E4-E6C48D2D0686Q38309670-7ACC4621-6224-4E18-932B-9C6ECDAF8772Q38343693-2B805439-1EEE-4790-95C5-AE34F3542D4FQ38364041-1401E376-E876-4F30-AF46-40AF5D17DFEAQ40397571-E2F7C138-EDEF-4AE6-9E15-BBD16EB2D46AQ40453109-C869A961-3AE3-429E-8298-D06830F4D7AFQ40537582-E4F90475-CBBB-4E81-AEEA-7F1A5DC0D64CQ40559782-C06911A8-F1B3-456B-8274-62BCB8AB3FA5Q40631651-2E29D440-0E9E-4451-A787-01474FE79577Q40667984-83FCB4A7-DF02-491E-930F-DDED3D99B5CFQ40866660-BA17ECB2-9048-47FC-A66D-D09AC951C261Q40875735-BB24BC57-3A81-4D2C-B9E4-3829491C6F1BQ40953637-79F1C0BC-8C5C-476E-974C-D67245A61633Q42505325-5CC9DB0D-CC7C-412B-AFF6-6A995BBC3F71Q42538760-00A9AC8A-BF4A-4ACC-A005-03273CE7E947Q42591638-673E3122-1B85-407F-A6C2-D933ECE3ABD4Q42815442-5EC71986-7205-4F93-AC07-B6EA5B2C71CCQ42849718-E671B479-DB0C-416D-AF3A-77E8646B9F1BQ43854340-F7C3B70E-7126-4928-85F8-EDA90B2E372A
P2860
Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Multiple modulation pathways o ...... icking of the alpha1C subunit.
@ast
Multiple modulation pathways o ...... icking of the alpha1C subunit.
@en
type
label
Multiple modulation pathways o ...... icking of the alpha1C subunit.
@ast
Multiple modulation pathways o ...... icking of the alpha1C subunit.
@en
prefLabel
Multiple modulation pathways o ...... icking of the alpha1C subunit.
@ast
Multiple modulation pathways o ...... icking of the alpha1C subunit.
@en
P2093
P2860
P356
P1476
Multiple modulation pathways o ...... icking of the alpha1C subunit.
@en
P2093
P2860
P304
19348-19356
P356
10.1074/JBC.273.30.19348
P407
P577
1998-07-01T00:00:00Z