Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages.
about
Monocytes in myocardial infarctionMultifaceted roles of STIM proteinsOlive (Olea europaea) leaf extract induces apoptosis and monocyte/macrophage differentiation in human chronic myelogenous leukemia K562 cells: insight into the underlying mechanism.Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healingKrox20/EGR2 deficiency accelerates cell growth and differentiation in the monocytic lineage and decreases bone massRegulation and consequences of monocytosisSampling-dependent up-regulation of gene expression in sequential samples of human airway epithelial cells.In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis.Leukemic marrow infiltration reveals a novel role for Egr3 as a potent inhibitor of normal hematopoietic stem cell proliferation.Role of Erk1/2 signaling in the regulation of neutrophil versus monocyte development in response to G-CSF and M-CSF.Expression of Egr-1, c-fos and cyclin D1 in esophageal cancer and its precursors: An immunohistochemical and in situ hybridization studyTiming of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.Early growth response genes regulate B cell development, proliferation, and immune response.The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cellsM-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrowMonocyte and macrophage dynamics during atherogenesis.Computational identification of the normal and perturbed genetic networks involved in myeloid differentiation and acute promyelocytic leukemia.Mechanisms of self-renewal in hematopoietic stem cells.Instructive role of M-CSF on commitment of bipotent myeloid cells involves ERK-dependent positive and negative signaling.Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts.Leukemia suppressor function of Egr-1 is dependent on transforming oncogene.The histone demethylase KDM5b/JARID1b plays a role in cell fate decisions by blocking terminal differentiation.Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia.Gene expression profiles of erythroid precursors characterise several mechanisms of the action of hydroxycarbamide in sickle cell anaemia.The interferon-inducible gene, Ifi204, is transcriptionally activated in response to M-CSF, and its expression favors macrophage differentiation in myeloid progenitor cells.Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation.The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice.Commonly dysregulated genes in murine APL cells.Loss of Egr1, a human del5q gene, accelerates BCR-ABL driven chronic myelogenous leukemia.Deficiency of CREB and over expression of miR-183 in juvenile myelomonocytic leukemia.The early growth response factor-1 contributes to interleukin-13 production by mast cells in response to stem cell factor stimulation.Novel regulators in hematopoietic stem cells can be revealed by a functional approach under leukemic condition.
P2860
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P2860
Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Early growth response gene 1 s ...... locyte and erythroid lineages.
@ast
Early growth response gene 1 s ...... locyte and erythroid lineages.
@en
type
label
Early growth response gene 1 s ...... locyte and erythroid lineages.
@ast
Early growth response gene 1 s ...... locyte and erythroid lineages.
@en
prefLabel
Early growth response gene 1 s ...... locyte and erythroid lineages.
@ast
Early growth response gene 1 s ...... locyte and erythroid lineages.
@en
P2093
P356
P1433
P1476
Early growth response gene 1 s ...... locyte and erythroid lineages.
@en
P2093
Krishnaraju K
Liebermann DA
P304
P356
10.1182/BLOOD.V97.5.1298
P407
P577
2001-03-01T00:00:00Z