p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice. - Test2 - elhamkhani - TriplyDB

p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice.

p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice.

http://www.wikidata.org/entity/Q33186542

about

EAPP, a novel E2F binding protein that modulates E2F-dependent transcription A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity p14ARF expression in invasive breast cancers and ductal carcinoma in situ--relationships to p53 and Hdm2 Divorcing ARF and p53: an unsettled case Tumor suppressor ARF inhibits HER-2/neu-mediated oncogenic growth Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms.Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.Live-cell imaging of caspase activation for high-content screening Human papillomavirus 16 oncoprotein E7 stimulates UBF1-mediated rDNA gene transcription, inhibiting a p53-independent activity of p14ARF ARF-induced downregulation of Mip130/LIN-9 protein levels mediates a positive feedback that leads to increased expression of p16Ink4a and p19Arf.Human tumor suppressor p14ARF negatively regulates rRNA transcription and inhibits UBF1 transcription factor phosphorylation.TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer Dynamics of ARF regulation that control senescence and cancer.p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B.Alternative splicing of the human cyclin D-binding Myb-like protein (hDMP1) yields a truncated protein isoform that alters macrophage differentiation patterns.Nucleostemin stabilizes ARF by inhibiting the ubiquitin ligase ULF.A meta-analysis of the relationship between FGFR3 and TP53 mutations in bladder cancer.p14ARF activates a Tip60-dependent and p53-independent ATM/ATR/CHK pathway in response to genotoxic stress p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop.The association of transporter genes polymorphisms and lung cancer chemotherapy response A 12-gene genomic instability signature predicts clinical outcomes in multiple cancer types.Selective requirement of H2B N-Terminal tail for p14ARF-induced chromatin silencing.Gene therapy progress and prospects: cancer gene therapy using tumour suppressor genes.Mitochondrial p32 is a critical mediator of ARF-induced apoptosis P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3.MicroRNA-155 promotes bladder cancer growth by repressing the tumor suppressor DMTF1.ARF-BP1 as a potential therapeutic target Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities p53 and p16Ink4a/p19Arf Loss Promotes Different Pancreatic Tumor Types from PyMT-Expressing Progenitor Cells A genotoxic stress-responsive miRNA, miR-574-3p, delays cell growth by suppressing the enhancer of rudimentary homolog gene in vitro.The emerging role of Mule and ARF in the regulation of base excision repair.Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells.Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival.Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase.p14(ARF) inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway.RUVBL2 is a novel repressor of ARF transcription.Characterization of the gene structure, functional significance, and clinical application of RNF180, a novel gene in gastric cancer.

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p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice.

http://www.wikidata.org/entity/Q33186542

description

2003 nî lūn-bûn

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2003 թուականի Մարտին հրատարակուած գիտական յօդուած

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2003 թվականի մարտին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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name

p14ARF induces G2 arrest and a ...... ours established in nude mice.

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p14ARF induces G2 arrest and a ...... ours established in nude mice.

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p14ARF induces G2 arrest and a ...... ours established in nude mice.

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p14ARF induces G2 arrest and a ...... ours established in nude mice.

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Béatrice Eymin

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Camille Leduc

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Jean-Luc Coll

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Sylvie Gazzeri

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P2860

Structural basis of cyclin-dependent kinase activation by phosphorylation

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.

Cdc2 regulatory factors.

p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation.

p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

TUNEL apoptotic cell detection in tissue sections: critical evaluation and improvement.

Mechanism of ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin keratinocytes with defective p53.

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1822-1835

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Elisabeth Brambilla

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7820117

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1043009363

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12660818

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