The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
about
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparumOn the molecular mechanism of chloroquine's antimalarial actionPlasmodium falciparum enolase: stage-specific expression and sub-cellular localizationCopper pathways in Plasmodium falciparum infected erythrocytes indicate an efflux role for the copper P-ATPaseRecombinant vacuolar iron transporter family homologue PfVIT from human malaria-causing Plasmodium falciparum is a Fe(2+)/H(+)exchangerMalarial hemozoin: from target to toolCrystal structures from the Plasmodium peroxiredoxins: new insights into oligomerization and product binding.Overcoming the heme paradox: heme toxicity and tolerance in bacterial pathogens.Hemozoin accumulation in Garnham bodies of Plasmodium falciparum gametocytes.Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes.Food vacuole associated enolase in plasmodium undergoes multiple post-translational modifications: evidence for atypical ubiquitination.Potent antihematozoan activity of novel bisthiazolium drug T16: evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.Potentiation of an antimalarial oxidant drug.A non-cytotoxic N-dehydroabietylamine derivative with potent antimalarial activityPlasmodium falciparum enolase complements yeast enolase functions and associates with the parasite food vacuole.Sontochin as a guide to the development of drugs against chloroquine-resistant malaria.Ubiquitin-like modifiers and their deconjugating enzymes in medically important parasitic protozoa.Inhibition of hemozoin formation in Plasmodium falciparum trophozoite extracts by heme analogs: possible implication in the resistance to malaria conferred by the beta-thalassemia trait.Novel antimalarial drug targets: hope for new antimalarial drugs.Expression and characterisation of plasmepsin I from Plasmodium falciparum.Effect of piplartine and cinnamides on Leishmania amazonensis, Plasmodium falciparum and on peritoneal cells of Swiss mice.Optimization of xanthones for antimalarial activity: the 3,6-bis-omega-diethylaminoalkoxyxanthone series.Erythrocyte membranes convert monomeric ferriprotoporphyrin IX to β-hematin in acidic environment at malarial fever temperature.Evaluation of pH during cytostomal endocytosis and vacuolar catabolism of haemoglobin in Plasmodium falciparum.Matrix Metalloproteinase-9 and Haemozoin: Wedding Rings for Human Host and Plasmodium falciparum Parasite in Complicated MalariaNew insight into the mechanism of accumulation and intraerythrocytic compartmentation of albitiazolium, a new type of antimalarial.Involvement of heme in the antimalarial action of chloroquine.Xanthones as antimalarial agents; studies of a possible mode of action.Antimalarial activity of newly synthesized chalcone derivatives in vitro.Genetic disruption of the Plasmodium falciparum digestive vacuole plasmepsins demonstrates their functional redundancy.Quantitative calcium measurements in subcellular compartments of Plasmodium falciparum-infected erythrocytes.The catalytic significance of the proposed active site residues in Plasmodium falciparum histoaspartic protease.High-Content Screening of MMV Pathogen Box for Plasmodium falciparum Digestive Vacuole Disrupting Molecules Reveals Valuable Starting Points for Drug Discovery.Biosynthesis and maturation of the malaria aspartic hemoglobinases plasmepsins I and II.Disruption of the Plasmodium falciparum 2-Cys peroxiredoxin gene renders parasites hypersensitive to reactive oxygen and nitrogen species.
P2860
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P2860
The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
@ast
The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
@en
type
label
The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
@ast
The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
@en
prefLabel
The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
@ast
The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
@en
P1476
The plasmodium digestive vacuole: metabolic headquarters and choice drug target.
@en
P2093
Goldberg DE
Olliaro PL
P304
P356
10.1016/0169-4758(95)80042-5
P577
1995-08-01T00:00:00Z