DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila. - Test2 - elhamkhani - TriplyDB

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

http://www.wikidata.org/entity/Q33205672

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Epithelial cell polarity: a major gatekeeper against cancer?Cell polarity signaling in the plasticity of cancer cell invasiveness Epithelial cell polarity determinant CRB3 in cancer development Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling.A conserved polybasic domain mediates plasma membrane targeting of Lgl and its regulation by hypoxia The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state Domain-specific functions of Stardust in Drosophila embryonic development Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex Structural basis for the phosphorylation-regulated interaction between the cytoplasmic tail of cell polarity protein crumbs and the actin-binding protein moesin The PAR proteins: fundamental players in animal cell polarization.aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development The apicobasal polarity kinase aPKC functions as a nuclear determinant and regulates cell proliferation and fate during Xenopus primary neurogenesis.Radial intercalation is regulated by the Par complex and the microtubule-stabilizing protein CLAMP/Spef1.CRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium.Apposition of iroquois expressing and non-expressing cells leads to cell sorting and fold formation in the Drosophila imaginal wing disc.Scribble mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs.Genetic interactions between the Drosophila tumor suppressor gene ept and the stat92E transcription factor.Functional interactions between the erupted/tsg101 growth suppressor gene and the DaPKC and rbf1 genes in Drosophila imaginal disc tumors A modifier screen for Bazooka/PAR-3 interacting genes in the Drosophila embryo epithelium.Trafficking through COPII stabilises cell polarity and drives secretion during Drosophila epidermal differentiation.Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase Multiple domains in the Crumbs Homolog 2a (Crb2a) protein are required for regulating rod photoreceptor size.Drosophila VHL tumor-suppressor gene regulates epithelial morphogenesis by promoting microtubule and aPKC stability Genetic interaction of centrosomin and bazooka in apical domain regulation in Drosophila photoreceptor.Tissue polarity-dependent control of mammary epithelial homeostasis and cancer development: an epigenetic perspective.aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers Establishment of epithelial polarity--GEF who's minding the GAP?Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling Formation of a Bazooka-Stardust complex is essential for plasma membrane polarity in epithelia The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila Organogenesis and tumorigenesis: insight from the JAK/STAT pathway in the Drosophila eye The F-box protein Slmb restricts the activity of aPKC to polarize epithelial cells Anisotropy of Crumbs and aPKC drives myosin cable assembly during tube formation.Nuf and Rip11 requirement for polarity determinant recycling during Drosophila development.Protein kinase C-dependent signaling controls the midgut epithelial barrier to malaria parasite infection in anopheline mosquitoes Novel neuroprotective function of apical-basal polarity gene crumbs in amyloid beta 42 (aβ42) mediated neurodegeneration Identification of novel Ras-cooperating oncogenes in Drosophila melanogaster: a RhoGEF/Rho-family/JNK pathway is a central driver of tumorigenesis.Localization and Function of Pals1-associated Tight Junction Protein in Drosophila Is Regulated by Two Distinct Apical Complexes

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P2860

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

http://www.wikidata.org/entity/Q33205672

description

2004 nî lūn-bûn

@nan

2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի օգոստոսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

DaPKC-dependent phosphorylatio ...... l cell polarity in Drosophila.

@ast

DaPKC-dependent phosphorylatio ...... l cell polarity in Drosophila.

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type

label

DaPKC-dependent phosphorylatio ...... l cell polarity in Drosophila.

@ast

DaPKC-dependent phosphorylatio ...... l cell polarity in Drosophila.

@en

prefLabel

DaPKC-dependent phosphorylatio ...... l cell polarity in Drosophila.

@ast

DaPKC-dependent phosphorylatio ...... l cell polarity in Drosophila.

@en

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P1433

Journal of Cell Biology

P1476

DaPKC-dependent phosphorylatio ...... al cell polarity in Drosophila

@en

P2093

Eva Caminero

http://www.w3.org/2001/XMLSchema#string

Jorge Moscat

http://www.w3.org/2001/XMLSchema#string

María Teresa Díaz-Meco

http://www.w3.org/2001/XMLSchema#string

Sonsoles Campuzano

http://www.w3.org/2001/XMLSchema#string

P2860

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation.

Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures

The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

Direct interaction of two polarity complexes implicated in epithelial tight junction assembly

Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity

CRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cells

An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells

P304

549-557

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scholarly article

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10.1083/JCB.200311031

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4

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P478

166

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P577

2004-08-09T00:00:00Z

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8408021

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P698

15302858

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P921

phosphorylation

P932

2172211

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