Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors.
about
Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons.Unexpected neuronal protection of SU5416 against 1-Methyl-4-phenylpyridinium ion-induced toxicity via inhibiting neuronal nitric oxide synthaseHeterologous expression and biochemical characterisation of fourteen esterases from Helicoverpa armigeraThe anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOSNeuroprotective effects of bis(7)-tacrine against glutamate-induced retinal ganglion cells damage.Assessment of Neuronal Viability Using Fluorescein Diacetate-Propidium Iodide Double Staining in Cerebellar Granule Neuron Culture.Cholinergic deficiency involved in vascular dementia: possible mechanism and strategy of treatment.Pathologically activated neuroprotection via uncompetitive blockade of N-methyl-D-aspartate receptors with fast off-rate by novel multifunctional dimer bis(propyl)-cognitin.Donepezil in Alzheimer's disease: From conventional trials to pharmacogeneticsSunitinib produces neuroprotective effect via inhibiting nitric oxide overproduction.Protection against β-amyloid-induced synaptic and memory impairments via altering β-amyloid assembly by bis(heptyl)-cognitinGardenamide A Protects RGC-5 Cells from H₂O₂-Induced Oxidative Stress Insults by Activating PI3K/Akt/eNOS Signaling PathwayActivation of transcription factor MEF2D by bis(3)-cognitin protects dopaminergic neurons and ameliorates Parkinsonian motor defects.Targeting acetylcholinesterase to treat neurodegeneration.Novel anti-Alzheimer's dimer Bis(7)-cognitin: cellular and molecular mechanisms of neuroprotection through multiple targets.Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease.Antioxidant drug therapy approaches for neuroprotection in chronic diseases of the retina.Dual inhibition: a novel promising pharmacological approach for different disease conditions.Beta-secretase as a target for Alzheimer's disease drug discovery: an overview of in vitro methods for characterization of inhibitors.The novel tetramethylpyrazine bis-nitrone (TN-2) protects against MPTP/MPP+-induced neurotoxicity via inhibition of mitochondrial-dependent apoptosis.Sulfuretin Attenuates MPP⁺-Induced Neurotoxicity through Akt/GSK3β and ERK Signaling Pathways.Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excitotoxicity mediated by N-methyl-D-aspartate receptors.Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels.Neuroprotective effects ofEriobotrya japonicaandSalvia miltiorrhizaBunge inin vitroandin vivomodels
P2860
Q27349717-879AAC9E-C1D6-4B4D-A783-F8907C63FC27Q28484004-35CCDB8C-3508-48E7-BD18-2DD60D5C94FDQ28533969-4D239F01-0BFB-4C15-848D-BBF010CC23B6Q28583196-D449919C-C621-4732-AFB1-94AD8E47ABFCQ30978745-D625E96C-079F-4D2C-91D7-FFFDC1DF8C32Q32177114-A3F2B7E6-2211-4DE1-9ECD-1C3810B4EBC1Q33552656-9FA29358-2624-4574-8178-BD9F27F56AA9Q33924304-477B2EAB-3D45-4206-A116-D8F8E0242C11Q34965949-2359880E-4C51-4D1C-9883-9CAA7B383D46Q35083762-2C7B8DE9-F503-4096-9224-D6D67603E22AQ35868960-79A9297E-48A3-428C-A55D-D8C48BBDB23EQ36184230-A95829E7-0612-4630-B16E-347F64484A0BQ36298388-5B68AA62-28C5-48E5-808E-43EE3AE49B60Q36709537-B5602190-72E4-4C55-AEBA-ED7917D3F374Q37358683-0C01C28F-0E04-4C5F-8E1F-EA7262BAFFAFQ37559812-A56FDF6D-9B6E-46AE-A034-6E1AEF52F923Q37645117-58BC4EFD-EFC6-478D-96C5-0BD9AFC28C06Q37852762-8B218F4D-3BBF-4937-86FF-02C9E01544FEQ37866692-D4CE28D3-A06C-45AF-A131-573248E60F5DQ39063048-DCD686E2-24AD-4BD8-9536-19B99FFFEDBAQ46236697-53359DFC-7473-4A96-A5CB-EA778A88CEDDQ48361521-CF2C61AA-C3AD-41E9-9129-A916FB967ADBQ48498159-FEC634B6-40EF-4CCE-B97B-85B0E2DC485DQ58283823-6C6111C5-1DAD-41B3-B670-D70952D79464
P2860
Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Novel dimeric acetylcholineste ...... -methyl-D-aspartate receptors.
@ast
Novel dimeric acetylcholineste ...... -methyl-D-aspartate receptors.
@en
type
label
Novel dimeric acetylcholineste ...... -methyl-D-aspartate receptors.
@ast
Novel dimeric acetylcholineste ...... -methyl-D-aspartate receptors.
@en
prefLabel
Novel dimeric acetylcholineste ...... -methyl-D-aspartate receptors.
@ast
Novel dimeric acetylcholineste ...... -methyl-D-aspartate receptors.
@en
P2093
P2860
P50
P356
P1476
Novel dimeric acetylcholineste ...... -methyl-D-aspartate receptors.
@en
P2093
Chaoying Li
Donald C Chang
Hing Wai Tsang
Hugh H N Chan
Jialie Luo
Karl W K Tsim
Keming Xiong
Mingtao Li
Nelson T K Lee
Rongbiao Pi
P2860
P304
18179-18188
P356
10.1074/JBC.M411085200
P407
P577
2005-02-14T00:00:00Z