Semi-synthetic DNA shuffling of aveC leads to improved industrial scale production of doramectin by Streptomyces avermitilis.
about
Biocatalytic conversion of avermectin to 4''-oxo-avermectin: improvement of cytochrome p450 monooxygenase specificity by directed evolution.Drug discovery and natural products: end of an era or an endless frontier?Recent developments in antibacterial drug discovery: microbe-derived natural products--from collection to the clinic.Incorporating Synthetic Oligonucleotides via Gene Reassembly (ISOR): a versatile tool for generating targeted libraries.Optimization of combinatorial mutagenesis.Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture.Directed Evolution: Past, Present and Future.Site-directed mutant libraries for isolating minimal mutations yielding functional changes.Natural products and Pharma 2011: strategic changes spur new opportunities.Recent advances in biochemistry and biotechnological synthesis of avermectins and their derivatives.Directed evolution 2.0: improving and deciphering enzyme properties.Engineering microbial hosts for production of bacterial natural productsA biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid.Co-overexpression of lmbW and metK led to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain of Streptomyces lincolnensis.Four new doramectin congeners with acaricidal and insecticidal activity from Streptomyces avermitilis NEAU1069.Significance of Heavy-Ion Beam Irradiation-Induced Avermectin B1a Production by Engineered Streptomyces avermitilis.Interrogation of Streptomyces avermitilis for efficient production of avermectins.Streptomycin resistance-aided genome shuffling to improve doramectin productivity of Streptomyces avermitilis NEAU1069.
P2860
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P2860
Semi-synthetic DNA shuffling of aveC leads to improved industrial scale production of doramectin by Streptomyces avermitilis.
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2005 nî lūn-bûn
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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
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name
Semi-synthetic DNA shuffling o ...... n by Streptomyces avermitilis.
@ast
Semi-synthetic DNA shuffling o ...... n by Streptomyces avermitilis.
@en
type
label
Semi-synthetic DNA shuffling o ...... n by Streptomyces avermitilis.
@ast
Semi-synthetic DNA shuffling o ...... n by Streptomyces avermitilis.
@en
prefLabel
Semi-synthetic DNA shuffling o ...... n by Streptomyces avermitilis.
@ast
Semi-synthetic DNA shuffling o ...... n by Streptomyces avermitilis.
@en
P2093
P1476
Semi-synthetic DNA shuffling o ...... in by Streptomyces avermitilis
@en
P2093
Anke Krebber
Charlene La
Hamish McArthur
Katja Pekrun
Kim Stutzman-Engwall
Richard Fox
Ronald Fedechko
Stephane Jenne
P356
10.1016/J.YMBEN.2004.07.003
P577
2005-01-01T00:00:00Z