Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
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Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insightsEvolution of lanthipeptide synthetasesStructure-activity relationship studies of the two-component lantibiotic haloduracinCyclisation mechanisms in the biosynthesis of ribosomally synthesised and post-translationally modified peptidesDiscovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.Production of dehydroamino acid-containing peptides by Lactococcus lactis.On the substrate specificity of dehydration by lacticin 481 synthetaseThe leader peptide is not required for post-translational modification by lacticin 481 synthetase.Manipulation of thiocillin variants by prepeptide gene replacement: structure, conformation, and activity of heterocycle substitution mutants.Thiazolyl peptide antibiotic biosynthesis: a cascade of post-translational modifications on ribosomal nascent proteins.Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.Unusual acetylation-elimination in the formation of tetronate antibiotics.In vitro activity of the nisin dehydratase NisB.A price to pay for relaxed substrate specificity: a comparative kinetic analysis of the class II lanthipeptide synthetases ProcM and HalM2.Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin.Biosynthesis of the antimicrobial peptide epilancin 15X and its N-terminal lactateLantibiotic immunity: inhibition of nisin mediated pore formation by NisIMichael-type cyclizations in lantibiotic biosynthesis are reversible.Phosphoserine Lyase Deoxyribozymes: DNA-Catalyzed Formation of Dehydroalanine Residues in Peptides.The enterococcal cytolysin synthetase has an unanticipated lipid kinase foldMorphogenetic surfactants and their role in the formation of aerial hyphae in Streptomyces coelicolor.New Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products.Rings, radicals, and regeneration: the early years of a bioorganic laboratoryStructure and tRNA Specificity of MibB, a Lantibiotic Dehydratase from Actinobacteria Involved in NAI-107 Biosynthesis.Use of lantibiotic synthetases for the preparation of bioactive constrained peptidesMutants of the zinc ligands of lacticin 481 synthetase retain dehydration activity but have impaired cyclization activity.Mechanistic investigations of the dehydration reaction of lacticin 481 synthetase using site-directed mutagenesis.On the regioselectivity of thioether formation by lacticin 481 synthetaseLeader Peptide Establishes Dehydration Order, Promotes Efficiency, and Ensures Fidelity During Lacticin 481 Biosynthesis.In vitro reconstitution and substrate specificity of a lantibiotic protease.The importance of the leader sequence for directing lanthionine formation in lacticin 481.Lacticin 481 synthetase as a general serine/threonine kinase.Investigation of the substrate specificity of lacticin 481 synthetase by using nonproteinogenic amino acids.Distributive and directional behavior of lantibiotic synthetases revealed by high-resolution tandem mass spectrometry.Ribosomally synthesized and post-translationally modified peptide natural products: new insights into the role of leader and core peptides during biosynthesis.Restoration of bioactive lantibiotic suicin from a remnant lan locus of pathogenic Streptococcus suis serotype 2.Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds.Insights into the evolution of lanthipeptide biosynthesis.Substrate recognition and specificity of the NisB protein, the lantibiotic dehydratase involved in nisin biosynthesisMechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.
P2860
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P2860
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
description
2005 nî lūn-bûn
@nan
2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
@ast
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
@en
type
label
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
@ast
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
@en
prefLabel
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
@ast
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
@en
P2093
P356
P1476
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.
@en
P2093
Leah M Miller
Myongsin Yi
Neil L Kelleher
Yong L Leung
P304
15332-15333
P356
10.1021/JA0543043
P407
P577
2005-11-01T00:00:00Z