Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis.
about
IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activationNaturally Occurring Isothiocyanates Exert Anticancer Effects by Inhibiting Deubiquitinating EnzymesAnthraquinone G503 induces apoptosis in gastric cancer cells through the mitochondrial pathwaySynthesis and evaluation of derivatives of the proteasome deubiquitinase inhibitor b-AP15Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function.Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.Molecular Mechanism of Cinnamomum verum Component Cuminaldehyde Inhibits Cell Growth and Induces Cell Death in Human Lung Squamous Cell Carcinoma NCI-H520 Cells In Vitro and In VivoDNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions.Characterization of ubiquitin and ubiquitin-like-protein isopeptidase activities.The proteasome deubiquitinase inhibitor VLX1570 shows selectivity for ubiquitin-specific protease-14 and induces apoptosis of multiple myeloma cellsCinnamomum verum component 2-methoxycinnamaldehyde: a novel antiproliferative drug inducing cell death through targeting both topoisomerase I and II in human colorectal adenocarcinoma COLO 205 cells.Cuminaldehyde from Cinnamomum verum Induces Cell Death through Targeting Topoisomerase 1 and 2 in Human Colorectal Adenocarcinoma COLO 205 Cells.The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIBTargeting ubiquitination for cancer therapies.Emerging therapies targeting the ubiquitin proteasome system in cancerProteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks.1,5-diaryl-3-oxo-1,4-pentadienes: a case for antineoplastics with multiple targets.The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeuticsThe isopeptidase inhibitor 2cPE triggers proteotoxic stress and ATM activation in chronic lymphocytic leukemia cells.HIF-1α downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic mammalian orthoreovirus.Cinnamomum verum Component 2-Methoxycinnamaldehyde: A Novel Anticancer Agent with Both Anti-Topoisomerase I and II Activities in Human Lung Adenocarcinoma A549 Cells In Vitro and In Vivo.The DeISGylase USP18 limits TRAIL-induced apoptosis through the regulation of TRAIL levels: Cellular levels of TRAIL influences responsiveness to TRAIL-induced apoptosis.Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication.A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.Discovery of a novel anti-cancer agent targeting both topoisomerase I and II in hepatocellular carcinoma Hep 3B cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde.Isopeptidases in anticancer therapy: looking for inhibitors.A receptor-interacting protein 1 (RIP1)-independent necrotic death under the control of protein phosphatase PP2A that involves the reorganization of actin cytoskeleton and the action of cofilin-1.Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors.Flavonoid-enriched apple fraction AF4 induces cell cycle arrest, DNA topoisomerase II inhibition, and apoptosis in human liver cancer HepG2 cells.Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.The binding landscape of a partially-selective isopeptidase inhibitor with potent pro-death activity, based on the bis(arylidene)cyclohexanone scaffold.
P2860
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P2860
Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Identification of new compound ...... pase activation and apoptosis.
@ast
Identification of new compound ...... pase activation and apoptosis.
@en
Identification of new compound ...... pase activation and apoptosis.
@nl
type
label
Identification of new compound ...... pase activation and apoptosis.
@ast
Identification of new compound ...... pase activation and apoptosis.
@en
Identification of new compound ...... pase activation and apoptosis.
@nl
prefLabel
Identification of new compound ...... pase activation and apoptosis.
@ast
Identification of new compound ...... pase activation and apoptosis.
@en
Identification of new compound ...... pase activation and apoptosis.
@nl
P2093
P1433
P1476
Identification of new compound ...... spase activation and apoptosis
@en
P2093
Alessandra Fontanini
Barbara Solazzo
Clare J Henderson
Emanuela Aleo
P304
P356
10.1158/0008-5472.CAN-06-0702
P407
P577
2006-09-01T00:00:00Z