Genome-wide functional analysis of human cell-cycle regulators.
about
An integrated approach to elucidate the intra-viral and viral-cellular protein interaction networks of a gamma-herpesvirusIntegrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cellsGenomic screening with RNAi: results and challengesNarrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypesIntegrated functional, gene expression and genomic analysis for the identification of cancer targetsHost modulators of H1N1 cytopathogenicityHigh-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markersThe oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entryIdentification of genes that are essential to restrict genome duplication to once per cell divisionOff-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replicationCyclebase 3.0: a multi-organism database on cell-cycle regulation and phenotypesCyclebase.org: version 2.0, an updated comprehensive, multi-species repository of cell cycle experiments and derived analysis resultsGenes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levelsA role for IkappaB kinase 2 in bipolar spindle assembly.Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning.Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assayMicrofluidics-integrated time-lapse imaging for analysis of cellular dynamics.Revealing molecular mechanisms by integrating high-dimensional functional screens with protein interaction data.Live-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control.High-throughput screening using siRNA (RNAi) libraries.A microtubule interactome: complexes with roles in cell cycle and mitosisA high-throughput assay for siRNA-based circadian screens in human U2OS cellsCellProfiler Analyst: data exploration and analysis software for complex image-based screensA human protein interaction network shows conservation of aging processes between human and invertebrate species.Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen.Automated microscopy for high-content RNAi screeningGenome-wide microarray evidence that 8-cell human blastomeres over-express cell cycle drivers and under-express checkpoints.High-throughput screens in diploid cells identify factors that contribute to the acquisition of chromosomal instabilityExploration of chromatic aberration for multiplanar imaging: proof of concept with implications for fast, efficient autofocus.RNA interference screen to identify pathways that enhance or reduce nonviral gene transfer during lipofection.Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM.Quantification of lipid droplets and associated proteins in cellular models of obesity via high-content/high-throughput microscopy and automated image analysis.A protein network-guided screen for cell cycle regulators in Drosophila.A high-throughput platform for lentiviral overexpression screening of the human ORFeome.Effects of hormone agonists on Sf9 cells, proliferation and cell cycle arrest.Targeting lymphatic vessel functions through tyrosine kinases.High-content siRNA screening for target identification and validation.A genome-wide resource of cell cycle and cell shape genes of fission yeastTranscription factor binding profiles reveal cyclic expression of human protein-coding genes and non-coding RNAs.
P2860
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P2860
Genome-wide functional analysis of human cell-cycle regulators.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Genome-wide functional analysis of human cell-cycle regulators.
@ast
Genome-wide functional analysis of human cell-cycle regulators.
@en
type
label
Genome-wide functional analysis of human cell-cycle regulators.
@ast
Genome-wide functional analysis of human cell-cycle regulators.
@en
prefLabel
Genome-wide functional analysis of human cell-cycle regulators.
@ast
Genome-wide functional analysis of human cell-cycle regulators.
@en
P2093
P2860
P356
P1476
Genome-wide functional analysis of human cell-cycle regulators
@en
P2093
Anthony P Orth
Charles Y Cho
Christopher Martin
Craig Mickanin
Dieter Huesken
Francois Natt
Joerg Lange
Jonathan Hall
Loren Miraglia
Lubica Supekova
P2860
P304
14819-14824
P356
10.1073/PNAS.0604320103
P407
P50
P577
2006-09-25T00:00:00Z