Mitochondrial oxidative stress causes hyperphosphorylation of tau.
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Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's diseaseKilling Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's DiseaseStress weakens prefrontal networks: molecular insults to higher cognitionMicroglial cell dysregulation in brain aging and neurodegenerationTherapeutic and diagnostic challenges for frontotemporal dementiaMetabolic disturbances in diseases with neurological involvementAlzheimer's pathogenesis and its link to the mitochondrionOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseThe Role of MAPT in Neurodegenerative Diseases: Genetics, Mechanisms and TherapyOxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutationsRapid changes in phospho-MAP/tau epitopes during neuronal stress: cofilin-actin rods primarily recruit microtubule binding domain epitopesAmeliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain InjuryOverexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's diseaseReduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease.Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition.Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease.Origins of Alzheimer's disease: reconciling cerebrospinal fluid biomarker and neuropathology data regarding the temporal sequence of amyloid-beta and tau involvement.PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease.Leveraging existing data sets to generate new insights into Alzheimer's disease biology in specific patient subsets.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Mitochondrial superoxide: a key player in Alzheimer's diseaseUpdate on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional miceBehavioral alterations are associated with vitamin B12 deficiency in the transcobalamin receptor/CD320 KO mouseMethylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicityMicroarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex.Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle.Convergence of amyloid-beta and tau pathologies on mitochondria in vivo.Lactate storm marks cerebral metabolism following brain traumaBlast exposure causes early and persistent aberrant phospho- and cleaved-tau expression in a murine model of mild blast-induced traumatic brain injuryBrain diabetic neurodegeneration segregates with low intrinsic aerobic capacityLoss of the m-AAA protease subunit AFG₃L₂ causes mitochondrial transport defects and tau hyperphosphorylation.Accelerating neuronal aging in in vitro model brain disorders: a focus on reactive oxygen speciesMitochondrial protection by the mixed muscarinic/σ1 ligand ANAVEX2-73, a tetrahydrofuran derivative, in Aβ25-35 peptide-injected mice, a nontransgenic Alzheimer's disease model.Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.Neuroprotective strategies involving ROS in Alzheimer disease.Reactive oxygen species in the regulation of synaptic plasticity and memory.A mitocentric view of Alzheimer's disease suggests multi-faceted treatmentsMitochondria and antioxidant targeted therapeutic strategies for Alzheimer's disease.
P2860
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P2860
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
@ast
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
@en
type
label
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
@ast
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
@en
prefLabel
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
@ast
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
@en
P2093
P2860
P50
P1433
P1476
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
@en
P2093
Alan Hubbard
Birgit Schilling
Brad Gibson
Christine Mavros
Doug Hinerfeld
Felicity Johnson
Karl Morten
Katrina Laughton
Paul A Adlard
Qiao-Xin Li
P2860
P356
10.1371/JOURNAL.PONE.0000536
P407
P577
2007-06-20T00:00:00Z