Mitochondrial oxidative stress causes hyperphosphorylation of tau. - Test2 - elhamkhani - TriplyDB

Mitochondrial oxidative stress causes hyperphosphorylation of tau.

Mitochondrial oxidative stress causes hyperphosphorylation of tau.

http://www.wikidata.org/entity/Q33288260

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Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer's Disease Stress weakens prefrontal networks: molecular insults to higher cognition Microglial cell dysregulation in brain aging and neurodegeneration Therapeutic and diagnostic challenges for frontotemporal dementia Metabolic disturbances in diseases with neurological involvement Alzheimer's pathogenesis and its link to the mitochondrion Oxidized cholesterol as the driving force behind the development of Alzheimer's disease The Role of MAPT in Neurodegenerative Diseases: Genetics, Mechanisms and Therapy Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations Rapid changes in phospho-MAP/tau epitopes during neuronal stress: cofilin-actin rods primarily recruit microtubule binding domain epitopes Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease.Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition.Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease.Origins of Alzheimer's disease: reconciling cerebrospinal fluid biomarker and neuropathology data regarding the temporal sequence of amyloid-beta and tau involvement.PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.Mitochondrial superoxide contributes to blood flow and axonal transport deficits in the Tg2576 mouse model of Alzheimer's disease.Leveraging existing data sets to generate new insights into Alzheimer's disease biology in specific patient subsets.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Mitochondrial superoxide: a key player in Alzheimer's disease Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice Behavioral alterations are associated with vitamin B12 deficiency in the transcobalamin receptor/CD320 KO mouse Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity Microarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex.Late-onset dementia: a mosaic of prototypical pathologies modifiable by diet and lifestyle.Convergence of amyloid-beta and tau pathologies on mitochondria in vivo.Lactate storm marks cerebral metabolism following brain trauma Blast exposure causes early and persistent aberrant phospho- and cleaved-tau expression in a murine model of mild blast-induced traumatic brain injury Brain diabetic neurodegeneration segregates with low intrinsic aerobic capacity Loss of the m-AAA protease subunit AFG₃L₂ causes mitochondrial transport defects and tau hyperphosphorylation.Accelerating neuronal aging in in vitro model brain disorders: a focus on reactive oxygen species Mitochondrial protection by the mixed muscarinic/σ1 ligand ANAVEX2-73, a tetrahydrofuran derivative, in Aβ25-35 peptide-injected mice, a nontransgenic Alzheimer's disease model.Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.Neuroprotective strategies involving ROS in Alzheimer disease.Reactive oxygen species in the regulation of synaptic plasticity and memory.A mitocentric view of Alzheimer's disease suggests multi-faceted treatments Mitochondria and antioxidant targeted therapeutic strategies for Alzheimer's disease.

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P2860

Mitochondrial oxidative stress causes hyperphosphorylation of tau.

http://www.wikidata.org/entity/Q33288260

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2007 nî lūn-bûn

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2007 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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Mitochondrial oxidative stress causes hyperphosphorylation of tau.

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Mitochondrial oxidative stress causes hyperphosphorylation of tau.

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Mitochondrial oxidative stress causes hyperphosphorylation of tau.

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Mitochondrial oxidative stress causes hyperphosphorylation of tau.

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Tau pathology in Alzheimer disease and other tauopathies

Probability-based protein identification by searching sequence databases using mass spectrometry data

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

Mitochondrial disease in superoxide dismutase 2 mutant mice

The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease

Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse

Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts

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