Interaction between T antigen and TEA domain of the factor TEF-1 derepresses simian virus 40 late promoter in vitro: identification of T-antigen domains important for transcription control
about
VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulationTranscription enhancer factor 1 interacts with a basic helix-loop-helix zipper protein, Max, for positive regulation of cardiac alpha-myosin heavy-chain gene expressionThe replication protein A binding site in simian virus 40 (SV40) T antigen and its role in the initial steps of SV40 DNA replication.Interaction of the transcription factor TFIID with simian virus 40 (SV40) large T antigen interferes with replication of SV40 DNA in vitro.The major transcriptional transactivation domain of simian virus 40 large T antigen associates nonconcurrently with multiple components of the transcriptional preinitiation complexTransactivation of a ribosomal gene by simian virus 40 large-T antigen requires at least three activities of the protein.A kinase activity associated with simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1Cell type-specific replication of simian virus 40 conferred by hormone response elements in the late promoter.The critical protein interactions and structures that elicit growth deregulation in cancer and viral replication.The J domain of papovaviral large tumor antigen is required for synergistic interaction with the POU-domain protein Tst-1/Oct6/SCIP.Protein kinase-A dependent phosphorylation of transcription enhancer factor-1 represses its DNA-binding activity but enhances its gene activation ability.An N-terminal deletion mutant of simian virus 40 (SV40) large T antigen oligomerizes incorrectly on SV40 DNA but retains the ability to bind to DNA polymerase alpha and replicate SV40 DNA in vitro.Activation of the human thymidine kinase (TK) promoter by simian virus 40 large T antigen requires both the T antigen pRb family-binding domain and TK promoter sequences resembling E2F-binding sites.Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations.
P2860
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P2860
Interaction between T antigen and TEA domain of the factor TEF-1 derepresses simian virus 40 late promoter in vitro: identification of T-antigen domains important for transcription control
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Interaction between T antigen ...... tant for transcription control
@ast
Interaction between T antigen ...... tant for transcription control
@en
Interaction between T antigen ...... ant for transcription control.
@nl
type
label
Interaction between T antigen ...... tant for transcription control
@ast
Interaction between T antigen ...... tant for transcription control
@en
Interaction between T antigen ...... ant for transcription control.
@nl
prefLabel
Interaction between T antigen ...... tant for transcription control
@ast
Interaction between T antigen ...... tant for transcription control
@en
Interaction between T antigen ...... ant for transcription control.
@nl
P2093
P2860
P1433
P1476
Interaction between T antigen ...... tant for transcription control
@en
P2093
P2860
P304
P577
1996-02-01T00:00:00Z