MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. - Test2 - elhamkhani - TriplyDB

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

http://www.wikidata.org/entity/Q33392688

about

Molecular pathology of emerging coronavirus infections Inflammatory monocytes and the pathogenesis of viral encephalitis Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection A decade after SARS: strategies for controlling emerging coronaviruses The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis.Interaction between innate immunity and porcine reproductive and respiratory syndrome virus.Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells.Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice.SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism.Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis Cellular immune responses to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in senescent BALB/c mice: CD4+ T cells are important in control of SARS-CoV infection.Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infection Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice.Immunogenicity and efficacy of a plasmid DNA rabies vaccine incorporating Myd88 as a genetic adjuvant.The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis.Effects of Toll-like receptor stimulation on eosinophilic infiltration in lungs of BALB/c mice immunized with UV-inactivated severe acute respiratory syndrome-related coronavirus vaccine.Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis.T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice.MTA1 coregulator regulates LPS response via MyD88-dependent signaling Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection.Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism MyD88 signaling is indispensable for primary influenza A virus infection but dispensable for secondary infection Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.Coronavirus non-structural protein 16: evasion, attenuation, and possible treatments.Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine.Kaposi's sarcoma-associated herpesvirus-encoded replication and transcription activator impairs innate immunity via ubiquitin-mediated degradation of myeloid differentiation factor 88 Epithelial cells lining salivary gland ducts are early target cells of severe acute respiratory syndrome coronavirus infection in the upper respiratory tracts of rhesus macaques.Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease.Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice.Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine.A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease.Mechanisms of severe acute respiratory syndrome coronavirus-induced acute lung injury.Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans Wild-type and innate immune-deficient mice are not susceptible to the Middle East respiratory syndrome coronavirus.Epigenetic Landscape during Coronavirus Infection The role of toll-like receptors in acute and chronic lung inflammation.

P2860

Q26824463-C964F402-547A-4E0B-AC6A-98A9F9904B62 Q26861256-01FB4577-7FE2-4780-B5F9-1E577DE41729 Q27488870-2888DE40-846E-461A-8A71-C5F9EAFE7A08 Q28817689-6F979C8A-A302-4AF4-932B-D8423A5ADD0B Q30234893-BF8F91EB-C508-4E02-BF6C-AB3B7778EBF0 Q30410415-5BE92833-4571-4ED9-9390-C5D81E5D228B Q33463837-6FFEA109-9B68-4C2E-A3F7-83F6D336AF00 Q33511964-4888240E-EF2E-446F-85D6-CA182B53C38D Q33553351-5EA59307-509E-4BF9-A71E-8B96241DAB0F Q33553636-147A9402-23CF-4FEC-AB48-CAB580CF1CCF Q33614444-4AEF67E7-B272-4827-9E96-39F6BE8A0C30 Q33676538-014043DB-812D-4168-B95D-5B8D4533475E Q33807608-50882968-696B-41E7-BA50-75406640B3A1 Q33850502-8F9F8EC4-3558-448F-91BB-A559D4FF2CE7 Q34047499-818635AE-9AC1-4F15-A443-66359C9D50CC Q34057901-18C7F52A-CE2F-4FB6-BDEF-8C688F2A27E3 Q34058136-423A0360-858B-4845-9132-AB7779E9BB5D Q34120055-4BE5E67A-F46C-42EE-8F8F-915478C06C45 Q34130797-10A19885-9D80-4BDF-9408-564B10B9A628 Q34152661-A00D62C1-672F-41EB-A61D-A512D23227E5 Q34190597-CF5CF30F-DA53-4739-ACBD-721DFA536A4B Q34190714-42E2C38E-A174-42B9-894E-AAB833D7265B Q34416382-D6A321DF-A35D-4E2E-8998-B7E3FA77E016 Q34457808-1646E3F4-9FEF-45AE-9927-173FA9242A0B Q34663663-6EA41E29-F207-4984-A359-A7F88F5876A2 Q34677842-37FF542D-F446-424C-A1CC-7C8C0D78C715 Q34992629-B0336C65-5FA4-4B6F-AE3D-2C23EC0A6C85 Q35076542-1BBFC67B-4D17-457A-B6C2-697306146A44 Q35660187-F3BE646E-AF96-474C-9603-EC14A06F60CF Q35665893-045BC46C-7552-48AB-AE2A-AA490885B6D3 Q35801738-282C2250-35C5-47A8-BAA0-903E72DB9497 Q36143370-376A4BE3-902D-4D96-B876-42525E1EE411 Q36216207-2A5EA67C-DDBB-4B3F-A7D1-547B51F993B1 Q36224671-98114F0D-48E9-4780-9504-9BA766E4D2C6 Q36456720-18B5D7D9-1A59-4C00-8BF4-115979AFDC34 Q37105639-7DA6A09B-67DF-4E4D-B516-E712966E4010 Q37119134-EFA63DEB-0990-45D3-935C-6F38498830E5 Q37565476-CA8DF409-0B3D-49C3-8946-C84C5784547C Q37727992-1A1AB6A1-59E9-4F99-BDF2-AF130908D76E Q37812405-CC14472E-9FAC-453A-B410-8C6C2CFFC7F8

P2860

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

http://www.wikidata.org/entity/Q33392688

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

@ast

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

@en

type

label

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

@ast

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

@en

prefLabel

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

@ast

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

@en

P1433

Q33392688-7AA55E6F-14D2-451B-B58D-1C6426E9F6E6

P1476

Q33392688-1571E357-2BB3-4FB9-815D-F9670CF8B1F4

P2093

Q33392688-0C81CEB3-62D9-4225-8C66-1BB5C64CD09A

Q33392688-284A9C12-7D1A-42E7-8155-94B713449520

Q33392688-6DBB2FD7-A115-4D79-A801-95178909A781

Q33392688-76B87742-85FF-45E7-BF0D-2F83487A9740

Q33392688-EFA91EC9-E9BB-4C5B-83DD-4638B4B3A366

P2860

Q33392688-08A7FADB-3E6E-4455-8F24-ABE4F40EAA13

Q33392688-14208906-0755-4DB8-AD27-D721E4F1DF66

Q33392688-220A954D-21BE-413C-B574-9547C3EF581D

Q33392688-24471547-A21F-4223-86B5-C907F7703EFB

Q33392688-2F5AC7A3-5969-4B26-B7D1-53BCBEE4BC1E

Q33392688-39BF01FE-A549-4535-8EFE-45595FC2DD95

Q33392688-41CB27C5-D670-47ED-9B6B-376ACC7B3F92

Q33392688-421C81EE-FFEC-4CB1-B92E-6BE22FE997ED

Q33392688-4640A321-CE4A-42D3-8E38-01E107A5EA25

Q33392688-4665CD39-C393-4878-88C4-39DC7155DB38

P304

Q33392688-42B90172-FE41-45EE-BA41-8FB19261264C

P31

Q33392688-5733A56E-1839-416A-B6AF-327790DBDC1D

P356

Q33392688-28CF47F9-C37C-4977-B984-2DBD3B4388E5

P433

Q33392688-FB569351-4AFE-4227-97EE-6C9450EBF9CF

P478

Q33392688-DCE152EF-89FD-4BC7-B514-0059AE4BB3E5

P50

Q33392688-1417546B-7836-4FEA-8F5C-95C065F256B8

Q33392688-45EE109C-6163-4DB0-881B-A71E1D427630

P577

Q33392688-E579C7B0-2308-4232-A7F1-9C6EF830079A

P5875

Q33392688-1DA706F7-6FFB-4BA2-B421-8C543E31632A

P698

Q33392688-203EB7CB-D33E-45E1-82E5-70457DE8A51F

P921

Q33392688-BAB17A1B-8472-49F9-903F-616BCE717E2E

Q33392688-F0C2B134-BCEA-4C77-B124-114E4D89BF5E

P932

Q33392688-85D1851E-6DEA-4C5C-B4F7-6F8437A7A0BB

P356

JOURNAL.PPAT.1000240

P1433

P1476

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

@en

P2093

Satoshi Uematsu

http://www.w3.org/2001/XMLSchema#string

Shizou Akira

http://www.w3.org/2001/XMLSchema#string

Thomas E Morrison

http://www.w3.org/2001/XMLSchema#string

Timothy Sheahan

http://www.w3.org/2001/XMLSchema#string

William Funkhouser

http://www.w3.org/2001/XMLSchema#string

P2860

Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection

Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS.

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes

An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity

Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants

Monocyte and macrophage heterogeneity

Blood monocytes consist of two principal subsets with distinct migratory properties

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

P304

e1000240

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PPAT.1000240

http://www.w3.org/2001/XMLSchema#string

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

4

http://www.w3.org/2001/XMLSchema#string

P50

P577

2008-12-12T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23660410

http://www.w3.org/2001/XMLSchema#string

P698

19079579

http://www.w3.org/2001/XMLSchema#string

P921

severe acute respiratory syndrome-related coronavirus

severe acute respiratory syndrome coronavirus

P932

2587915

http://www.w3.org/2001/XMLSchema#string