MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation.
about
Transcription factors in late megakaryopoiesis and related platelet disordersActin cytoskeletal defects in immunodeficiencyNeonatal expression of RNA-binding protein IGF2BP3 regulates the human fetal-adult megakaryocyte transition.Calpain 2 activation of P-TEFb drives megakaryocyte morphogenesis and is disrupted by leukemogenic GATA1 mutationInduction of megakaryocyte differentiation drives nuclear accumulation and transcriptional function of MKL1 via actin polymerization and RhoA activationCellular immune dysfunction in immune thrombocytopenia (ITP).Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defectsTranscriptional correlates of disease outcome in anticoagulant-treated non-human primates infected with ebolavirus.Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylationCell-autonomous function of Runx1 transcriptionally regulates mouse megakaryocytic maturation.MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development.Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosisSCL/TAL1-mediated transcriptional network enhances megakaryocytic specification of human embryonic stem cells.Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis.Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus.Immunodeficiency and severe susceptibility to bacterial infection associated with a loss-of-function homozygous mutation of MKL1.Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.The myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms.MRTFs- master regulators of EMT.Cadherin-11 is a novel regulator of extracellular matrix synthesis and tissue mechanicsMyocardin-related transcription factor A cooperates with brahma-related gene 1 to activate P-selectin transcription.Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.Megakaryocyte ontogeny: Clinical and molecular significance.MRTFA augments megakaryocyte maturation by enhancing the SRF regulatory axis
P2860
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P2860
MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
MKL1 and MKL2 play redundant a ...... ration and platelet formation.
@ast
MKL1 and MKL2 play redundant a ...... ration and platelet formation.
@en
type
label
MKL1 and MKL2 play redundant a ...... ration and platelet formation.
@ast
MKL1 and MKL2 play redundant a ...... ration and platelet formation.
@en
prefLabel
MKL1 and MKL2 play redundant a ...... ration and platelet formation.
@ast
MKL1 and MKL2 play redundant a ...... ration and platelet formation.
@en
P2093
P2860
P1433
P1476
MKL1 and MKL2 play redundant a ...... ration and platelet formation.
@en
P2093
Diane S Krause
Elenoe C Smith
Jonathan N Thon
Joseph E Italiano
Matthew T Devine
Patrick Gallagher
Sharon Lin
Stephanie A Massaro
Stephanie Halene
P2860
P304
P356
10.1182/BLOOD-2012-04-420828
P407
P577
2012-07-17T00:00:00Z