Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease - Test2 - elhamkhani - TriplyDB

Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease

Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease

http://www.wikidata.org/entity/Q33409853

about

Central role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human genetics A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates Novel biomarkers of fibrosis in Crohn's disease Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases Role of genetics in the diagnosis and prognosis of Crohn's disease Antimicrobial proteins in intestine and inflammatory bowel diseases Intestinal barrier in inflammatory bowel disease Lgr4 gene deficiency increases susceptibility and severity of dextran sodium sulfate-induced inflammatory bowel disease in mice Uncovering molecular biomarkers that correlate cognitive decline with the changes of hippocampus' gene expression profiles in Alzheimer's disease.Homeostasis of the gut barrier and potential biomarkers.Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon.Crohn disease: a current perspective on genetics, autophagy and immunity Mouse background strain profoundly influences Paneth cell function and intestinal microbial composition.Association of a functional variant in the Wnt co-receptor LRP6 with early onset ileal Crohn's disease Inflammatory bowel disease: an impaired barrier disease.Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms.Defensins couple dysbiosis to primary immunodeficiency in Crohn's disease.Antimicrobial peptides and gut microbiota in homeostasis and pathology.microRNAs as regulators of adipogenic differentiation of mesenchymal stem cells.Critical design aspects involved in the study of Paneth cells and the intestinal microbiota.Myeloid-derived suppressor cells in inflammatory bowel disease.Role of genetics in the diagnosis and prognosis of Crohn's disease Expansion of Paneth cell population in response to enteric Salmonella enterica serovar Typhimurium infection The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes Crohn's disease-derived monocytes fail to induce Paneth cell defensins Epithelial antimicrobial defence of the skin and intestine.Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo.Regulation of intestinal microbiota by the NLR protein family How does genotype influence disease phenotype in inflammatory bowel disease?Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis Mouse Paneth cell antimicrobial function is independent of Nod2.Susceptibility to infectious diseases based on antimicrobial peptide production.Role of gut microbiota in Crohn's disease.Multifunctional host defense peptides: antimicrobial peptides, the small yet big players in innate and adaptive immunity.The role of TLRs, NLRs, and RLRs in mucosal innate immunity and homeostasis.Innate antimicrobial immunity in inflammatory bowel diseases.From intestinal stem cells to inflammatory bowel diseases.Major signaling pathways in intestinal stem cells.microRNAs regulate adipocyte differentiation.

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P2860

Genetic variants of Wnt transcription factor TCF-4 (TCF7L2) putative promoter region are associated with small intestinal Crohn's disease

http://www.wikidata.org/entity/Q33409853

description

2009 nî lūn-bûn

@nan

2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Genetic variants of Wnt transc ...... all intestinal Crohn's disease

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Genetic variants of Wnt transc ...... all intestinal Crohn's disease

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type

label

Genetic variants of Wnt transc ...... all intestinal Crohn's disease

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Genetic variants of Wnt transc ...... all intestinal Crohn's disease

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prefLabel

Genetic variants of Wnt transc ...... all intestinal Crohn's disease

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Genetic variants of Wnt transc ...... all intestinal Crohn's disease

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JOURNAL.PONE.0004496

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Genetic variants of Wnt transc ...... all intestinal Crohn's disease

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Alexander Teml

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Charles L Bevins

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Derek Jewell

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Eduard F Stange

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Guoxing Wang

http://www.w3.org/2001/XMLSchema#string

Irmgard Kübler

http://www.w3.org/2001/XMLSchema#string

Julia Beisner

http://www.w3.org/2001/XMLSchema#string

Klaus Fellermann

http://www.w3.org/2001/XMLSchema#string

Klaus R Herrlinger

http://www.w3.org/2001/XMLSchema#string

Matthias Schwab

http://www.w3.org/2001/XMLSchema#string

P2860

Inflammatory Bowel Disease

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

Host-bacterial mutualism in the human intestine

Commensal host-bacterial relationships in the gut

Association of DLG5 and inflammatory bowel disease across populations

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

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scholarly article

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10.1371/JOURNAL.PONE.0004496

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2

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4

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Séverine Vermeire

Laurent Peyrin-Biroulet

Elke Schaeffeler

Rachel M Cooney

Mathias Chamaillard

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2009-02-16T00:00:00Z

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24019666

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19221600

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Crohn's disease

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2637978

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