Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
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A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cellsE Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV EvolutionBiology and therapy of inherited retinal degenerative disease: insights from mouse modelsGlial promoter selectivity following AAV-delivery to the immature brain.Optogenetics.Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulationAAV's anatomy: roadmap for optimizing vectors for translational successGFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectorsAn evolved adeno-associated viral variant enhances gene delivery and gene targeting in neural stem cellsEngineering liver-detargeted AAV9 vectors for cardiac and musculoskeletal gene transfer.A NEW RECOMBINANT ADENO-ASSOCIATED VIRUS (AAV)-BASED RANDOM PEPTIDE DISPLAY LIBRARY SYSTEM: INFECTION-DEFECTIVE AAV1.9-3 AS A NOVEL DETARGETED PLATFORM FOR VECTOR EVOLUTION.Directed evolution of adeno-associated virus for enhanced gene delivery and gene targeting in human pluripotent stem cells.Directed evolution of novel adeno-associated viruses for therapeutic gene delivery.Adeno-associated virus: fit to serveAdeno-associated virus (AAV) vectors in gene therapy: immune challenges and strategies to circumvent them.Synthetic virology: engineering viruses for gene deliveryAn adeno-associated virus-based intracellular sensor of pathological nuclear factor-κB activation for disease-inducible gene transfer.Novel properties of tyrosine-mutant AAV2 vectors in the mouse retinaAAV-mediated, optogenetic ablation of Müller Glia leads to structural and functional changes in the mouse retinaGene therapy for the nervous system: challenges and new strategies.High capsid-genome correlation facilitates creation of AAV libraries for directed evolutionTransforming growth factor α transforms astrocytes to a growth-supportive phenotype after spinal cord injuryEnhanced selective gene delivery to neural stem cells in vivo by an adeno-associated viral variantEfficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rho(-/-) mouseControlling AAV Tropism in the Nervous System with Natural and Engineered Capsids.The AAV vector toolkit: poised at the clinical crossroadsPulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries.A brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases.Optimization of design and production strategies for novel adeno-associated viral display peptide libraries.Creation of a cardiotropic adeno-associated virus: the story of viral directed evolution.Recent advances in RNA interference therapeutics for CNS diseases.CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypesWnt Regulates Proliferation and Neurogenic Potential of Müller Glial Cells via a Lin28/let-7 miRNA-Dependent Pathway in Adult Mammalian Retinas.Improved Adeno-associated Viral Gene Transfer to Murine Glioma.Progress and prospects: Immunobiology of gene therapy for neurodegenerative disease: prospects and risks.Novel adeno-associated viral vectors for retinal gene therapy.Viral vectors for gene delivery to the central nervous system.Regenerative nanomedicine and the treatment of degenerative retinal diseases.The advent of AAV9 expands applications for brain and spinal cord gene delivery.A next step in adeno-associated virus-mediated gene therapy for neurological diseases: regulation and targeting.
P2860
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P2860
Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
@ast
Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
@en
type
label
Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
@ast
Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
@en
prefLabel
Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
@ast
Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
@en
P2093
P2860
P50
P356
P1433
P1476
Molecular evolution of adeno-associated virus for enhanced glial gene delivery.
@en
P2093
Jae-Hyung Jang
James T Koerber
Ryan Klimczak
P2860
P304
P356
10.1038/MT.2009.184
P577
2009-08-11T00:00:00Z