Expanding small-molecule functional metagenomics through parallel screening of broad-host-range cosmid environmental DNA libraries in diverse proteobacteria.
about
Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small moleculesIntegrated (Meta) Genomic and Synthetic Biology Approaches to Develop New BiocatalystsDiscovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Metagenomics: Retrospect and Prospects in High Throughput AgeTargeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidatesBiotechnological applications of functional metagenomics in the food and pharmaceutical industriesBiocatalysts and small molecule products from metagenomic studiesIsolation of xylose isomerases by sequence- and function-based screening from a soil metagenomic libraryFunctional characterization of bacteria isolated from ancient arctic soil exposes diverse resistance mechanisms to modern antibioticsA plasmid toolkit for cloning chimeric cDNAs encoding customized fusion proteins into any Gateway destination expression vector.Metagenomic approaches to understanding phylogenetic diversity in quorum sensingSize Does Matter: Application-driven Approaches for Soil Metagenomics.Gram negative shuttle BAC vector for heterologous expression of metagenomic librariesMetagenomic analyses: past and future trends.Discovery of a metagenome-derived enzyme that produces branched-chain acyl-(acyl-carrier-protein)s from branched-chain α-keto acids.Functional metagenomic strategies for the discovery of novel enzymes and biosurfactants with biotechnological applications from marine ecosystems.Long-chain N-acyl amino acid synthases are linked to the putative PEP-CTERM/exosortase protein-sorting system in Gram-negative bacteriaThe great screen anomaly--a new frontier in product discovery through functional metagenomics.Viewing the human microbiome through three-dimensional glasses: integrating structural and functional studies to better define the properties of myriad carbohydrate-active enzymes.Metagenomic analysis of Streptomyces lividans reveals host-dependent functional expression.Mining the metabiome: identifying novel natural products from microbial communities.Prescreening bacterial colonies for bioactive molecules with Janus plates, a SBS standard double-faced microbial culturing system.Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of siderophore biosynthesis.Novel acid resistance genes from the metagenome of the Tinto River, an extremely acidic environment.Heterologous viral expression systems in fosmid vectors increase the functional analysis potential of metagenomic libraries.Deep sequencing of non-ribosomal peptide synthetases and polyketide synthases from the microbiomes of Australian marine sponges.Meta-omic characterization of prokaryotic gene clusters for natural product biosynthesis.Coupled high-throughput functional screening and next generation sequencing for identification of plant polymer decomposing enzymes in metagenomic librariesFirmicutes dominate the bacterial taxa within sugar-cane processing plants.New extremophilic lipases and esterases from metagenomicsAntibacterial enzymes from the functional screening of metagenomic libraries hosted in Ralstonia metalliduransProteomics as the final step in the functional metagenomics study of antimicrobial resistance.Synthetic biology approaches to improve biocatalyst identification in metagenomic library screening.Current functional metagenomic approaches only expand the existing protease sequence space, but does not presently add any novelty to it.Identification of novel esterase-active enzymes from hot environments by use of the host bacterium Thermus thermophilus.Strong spurious transcription likely contributes to DNA insert bias in typical metagenomic clone librariesFunctional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonistDiscovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.Current and future resources for functional metagenomicsFunctional Metagenomics of a Biostimulated Petroleum-Contaminated Soil Reveals an Extraordinary Diversity of Extradiol Dioxygenases.
P2860
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P2860
Expanding small-molecule functional metagenomics through parallel screening of broad-host-range cosmid environmental DNA libraries in diverse proteobacteria.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@ast
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@en
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@nl
type
label
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@ast
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@en
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@nl
prefLabel
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@ast
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@en
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@nl
P2093
P2860
P356
P1476
Expanding small-molecule funct ...... ies in diverse proteobacteria.
@en
P2093
Jeffrey H Kim
Sean F Brady
Steven C Obiajulu
P2860
P304
P356
10.1128/AEM.02169-09
P407
P577
2010-01-15T00:00:00Z