Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
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Caspase dependent programmed cell death in developing embryos: a potential target for therapeutic intervention against pathogenic nematodesObservation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitorAssay strategies for the discovery and validation of therapeutics targeting Brugia pahangi Hsp90Open-source approaches for the repurposing of existing or failed candidate drugs: learning from and applying the lessons across diseasesHigh sensitivity of Giardia duodenalis to tetrahydrolipstatin (orlistat) in vitroWhole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureusA target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodesA survey of current trends in computational drug repositioningRepositioning: the fast track to new anti-malarial medicines?Social sciences research in neglected tropical diseases 2: A bibliographic analysisDesign, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivityFinding promiscuous old drugs for new uses.Translating Nature's Library: The Bryostatins and Function-Oriented SynthesisExploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting.In vitro screening for drug repositioning.Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii.Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont.Old friends in new guise: repositioning of known drugs with structural bioinformatics.WIPO Re:Search: a consortium catalyzing research and product development for neglected tropical diseases.The Impact of Nurses on Neglected Tropical Disease Management.Drug repositioning using disease associated biological processes and network analysis of drug targets.Dual protonophore-chitinase inhibitors dramatically affect O. volvulus molting.A computational analysis of the binding mode of closantel as inhibitor of the Onchocerca volvulus chitinase: insights on macrofilaricidal drug design.Mining Filarial Genomes for Diagnostic and Therapeutic Targets.Alternative treatment strategies to accelerate the elimination of onchocerciasis.The multitargeted drug ivermectin: from an antiparasitic agent to a repositioned cancer drug.Impact of five annual rounds of mass drug administration with ivermectin on onchocerciasis in Sierra Leone.Current and Future Strategies for Improving Drug Discovery Efficiency
P2860
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P2860
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@ast
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@en
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@nl
type
label
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@ast
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@en
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@nl
prefLabel
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@ast
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@en
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@nl
P2093
P2860
P356
P1476
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
@en
P2093
Amanda L Garner
Christian Gloeckner
Fana Mersha
Gunnar F Kaufmann
Kim D Janda
Lisa M Eubanks
Nancy Tricoche
Yelena Oksov
P2860
P304
P356
10.1073/PNAS.0915125107
P407
P577
2010-02-08T00:00:00Z