TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells. - Test2 - elhamkhani - TriplyDB

TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells.

TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells.

http://www.wikidata.org/entity/Q33531352

about

Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.Role and relevance of TrkB mutations and expression in non-small cell lung cancer.Brain-derived neurotrophic factor expression predicts adverse pathological & clinical outcomes in human breast cancer.More expression of BDNF associates with lung squamous cell carcinoma and is critical to the proliferation and invasion of lung cancer cells.Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer.TrkB Promotes Breast Cancer Metastasis via Suppression of Runx3 and Keap1 Expression Apoptosis signal-regulating kinase 1 is involved in brain-derived neurotrophic factor (BDNF)-enhanced cell motility and matrix metalloproteinase 1 expression in human chondrosarcoma cells.MicroRNA-107 inhibits tumor growth and metastasis by targeting the BDNF-mediated PI3K/AKT pathway in human non-small lung cancer p75 neurotrophin receptor and pro-BDNF promote cell survival and migration in clear cell renal cell carcinoma.A network map of BDNF/TRKB and BDNF/p75NTR signaling system.Suppression of choriocarcinoma invasion and metastasis following blockade of BDNF/TrkB signaling.TrkB receptor signalling: implications in neurodegenerative, psychiatric and proliferative disorders.Neurotrophins and B-cell malignancies.Long noncoding nature brain-derived neurotrophic factor antisense is associated with poor prognosis and functional regulation in non-small cell lung caner.Cooperation of tyrosine kinase receptor TrkB and epidermal growth factor receptor signaling enhances migration and dispersal of lung tumor cells More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells.Constitutively active TrkB confers an aggressive transformed phenotype to a neural crest-derived cell line.High NUAK1 expression correlates with poor prognosis and involved in NSCLC cells migration and invasion.Knockdown of BDNF suppressed invasion of HepG2 and HCCLM3 cells, a mechanism associated with inactivation of RhoA or Rac1 and actin skeleton disorganization.Biological influence of brain-derived neurotrophic factor (BDNF) on colon cancer cells APRIL promotes non-small cell lung cancer growth and metastasis by targeting ERK1/2 signaling.Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer.Brain-derived neurotrophic factor/tropomyosin-related kinase B signaling pathway contributes to the aggressive behavior of lung squamous cell carcinoma.

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P2860

TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells.

http://www.wikidata.org/entity/Q33531352

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@ast

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@en

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@nl

type

label

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@ast

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@en

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@nl

prefLabel

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@ast

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@en

TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@nl

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1471-2407-10-43

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TrkB is highly expressed in NS ...... nd the invasion of A549 cells.

@en

P2093

Chunyan Li

http://www.w3.org/2001/XMLSchema#string

Dawei Guo

http://www.w3.org/2001/XMLSchema#string

Qingfu Zhang

http://www.w3.org/2001/XMLSchema#string

Siyang Zhang

http://www.w3.org/2001/XMLSchema#string

Wenting Luo

http://www.w3.org/2001/XMLSchema#string

Xueshan Qiu

http://www.w3.org/2001/XMLSchema#string

Yao Lu

http://www.w3.org/2001/XMLSchema#string

Ying Zhang

http://www.w3.org/2001/XMLSchema#string

Zeshi Cui

http://www.w3.org/2001/XMLSchema#string

P2860

Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation

RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion

RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner

RAFTK/Pyk2 regulates EGF-induced PC12 cell spreading and movement

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB

Up-regulation of Tropomyosin related kinase B contributes to resistance to detachment-induced apoptosis in hepatoma multicellular aggregations.

Expression of the neurotrophin receptor TrkB is associated with unfavorable outcome in Wilms' tumor.

Growth, survival and migration: the Trk to cancer.

Biological effects of TrkA and TrkB receptor signaling in neuroblastoma.

Targeting Akt to increase the sensitivity of neuroblastoma to chemotherapy: lessons learned from the brain-derived neurotrophic factor/TrkB signal transduction pathway.

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20156366

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