about
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinaseRecent progress on the role of Axl, a receptor tyrosine kinase, in malignant transformation of myeloid leukemiasERK2, but not ERK1, mediates acquired and "de novo" resistance to imatinib mesylate: implication for CML therapyRole of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations.TAM receptor tyrosine kinases: expression, disease and oncogenesis in the central nervous system.NUP98 gene rearrangements and the clonal evolution of chronic myelogenous leukemia.The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.Axl-targeted cancer imaging with humanized antibody h173.Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia.Axl as a mediator of cellular growth and survivalTAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.Role of proto-oncogene activation in carcinogenesis.High affinity molecules disrupting GRB2 protein complexes as a therapeutic strategy for chronic myelogenous leukaemia.Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.Molecular mechanisms in the evolution of chronic myelocytic leukemia.Progressive de novo DNA methylation at the bcr-abl locus in the course of chronic myelogenous leukemia.Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.bcr/abl and src but not myc and ras replace v-abl in lymphoid transformation.The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc.Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells.Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures.TAM receptors in leukemia: expression, signaling, and therapeutic implications.Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy.Molecular insights of Gas6/TAM in cancer development and therapy.Giving AXL the axe: targeting AXL in human malignancy.Increased tumor cell expression of Axl is a marker of aggressive features in breast cancer among African women.Structural elucidation of the DFG-Asp in and DFG-Asp out states of TAM kinases and insight into the selectivity of their inhibitors.Molecular analysis of Philadelphia chromosome positive leukaemiasDesign, Synthesis and Biological Evaluation of a Series of Novel Axl Kinase Inhibitors.The role of myc in transformation by BCR-ABL.Establishment and characterization of a new Ph1-positive chronic myeloid leukemia cell line MC3 with trilineage phenotype and an altered p53 gene.Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.High frequency of RAS oncogene mutation in chronic myeloid leukemia patients with myeloblastoma.Oncogenes and Anti-oncogenes in the Evolution of Human Leukemia/Lymphoma.Polymorphism T81C in H-RAS Oncogene Is Associated With Disease Progression in Imatinib (TKI) Treated Chronic Myeloid Leukemia Patients.Relapse into blast crisis following bone marrow transplantation for chronic phase chronic myeloid leukaemia: a report of five cases.Function of Axl receptor tyrosine kinase in non-small cell lung cancer.Sequential relapses of blastic crisis may involve different clones of cells with different molecular abnormalities.
P2860
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P2860
description
1988 nî lūn-bûn
@nan
1988 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի մարտին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Transforming genes in chronic myelogenous leukemia.
@ast
Transforming genes in chronic myelogenous leukemia.
@en
Transforming genes in chronic myelogenous leukemia.
@nl
type
label
Transforming genes in chronic myelogenous leukemia.
@ast
Transforming genes in chronic myelogenous leukemia.
@en
Transforming genes in chronic myelogenous leukemia.
@nl
prefLabel
Transforming genes in chronic myelogenous leukemia.
@ast
Transforming genes in chronic myelogenous leukemia.
@en
Transforming genes in chronic myelogenous leukemia.
@nl
P2093
P2860
P356
P1476
Transforming genes in chronic myelogenous leukemia.
@en
P2093
P2860
P304
P356
10.1073/PNAS.85.6.1952
P407
P577
1988-03-01T00:00:00Z