Homozygous disruption of the Tip60 gene causes early embryonic lethality. - Test2 - elhamkhani - TriplyDB

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

http://www.wikidata.org/entity/Q33570338

about

Epigenetic regulation of human embryonic stem cells Tip60 regulates myoblast differentiation by enhancing the transcriptional activity of MyoD via their physical interactions Lessons from genome-wide studies: an integrated definition of the coactivator function of histone acetyl transferases Targeting cancer using KAT inhibitors to mimic lethal knockouts Stress-induced cell-cycle activation in Tip60 haploinsufficient adult cardiomyocytes ATP dependent chromatin remodeling enzymes in embryonic stem cells p53 Acetylation: Regulation and Consequences HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development Tip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA.Rational design and validation of a Tip60 histone acetyltransferase inhibitor.KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency.Microarray analysis uncovers a role for Tip60 in nervous system function and general metabolism Chromatin modifiers and remodellers: regulators of cellular differentiation ATP-dependent chromatin remodeling: genetics, genomics and mechanisms.Partial loss of Tip60 slows mid-stage neurodegeneration in a spinocerebellar ataxia type 1 (SCA1) mouse model.Allele compensation in tip60+/- mice rescues white adipose tissue function in vivo.Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality.Distinct and redundant roles of the two MYST histone acetyltransferases Esa1 and Sas2 in cell growth and morphogenesis of Candida albicans.Roles for the Histone Modifying and Exchange Complex NuA4 in Cell Cycle Progression in Drosophila melanogaster.The acetyltransferase Tip60 contributes to mammary tumorigenesis by modulating DNA repair.Hdac6 regulates Tip60-p400 function in stem cells.Open chromatin in pluripotency and reprogramming Lysine Acetylation and Deacetylation in Brain Development and Neuropathies Tip60: connecting chromatin to DNA damage signaling.Crafting the brain - role of histone acetyltransferases in neural development and disease.Epigenetics in cardiac development, function, and disease.E3 ligase EDD1/UBR5 is utilized by the HPV E6 oncogene to destabilize tumor suppressor TIP60.KATapulting toward Pluripotency and Cancer.GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy.Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality.Tip60 complex binds to active Pol II promoters and a subset of enhancers and co-regulates the c-Myc network in mouse embryonic stem cells.Novel complex of HAT protein TIP60 and nuclear receptor PXR promotes cell migration and adhesion.Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production Baf53a is involved in survival of mouse ES cells, which can be compensated by Baf53b Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acetylation.Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate.TIP55, a splice isoform of the KAT5 acetyltransferase, is essential for developmental gene regulation and organogenesis

P2860

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P2860

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

http://www.wikidata.org/entity/Q33570338

description

2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@ast

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@en

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@nl

type

label

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@ast

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@en

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@nl

prefLabel

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@ast

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@en

Homozygous disruption of the Tip60 gene causes early embryonic lethality.

@nl

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Developmental Dynamics

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Homozygous disruption of the Tip60 gene causes early embryonic lethality.

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Donna McAllister

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John Lough

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Joseph B Fisher

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Min-Su Kim

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Stacy Koprowski

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Yaofei Hu

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P2860

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

Crif1 is a novel transcriptional coactivator of STAT3

Acetylation is indispensable for p53 activation

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

MOZ and MORF, two large MYSTic HATs in normal and cancer stem cells

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor

Cellular functions of TIP60

Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60

Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

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2912-2921

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10.1002/DVDY.22110

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11

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238

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19842187

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2801416

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