INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization. - Test2 - elhamkhani - TriplyDB

INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization.

INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization.

http://www.wikidata.org/entity/Q33590962

about

Phosphorylation at serine 331 is required for Aurora B activation.Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation Cell division: control of the chromosomal passenger complex in time and space Essential role of autoactivation circuitry on Aurora B-mediated H2AX-pS121 in mitosis Resetting a functional G1 nucleus after mitosis Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types Overexpression of hnRNPC2 induces multinucleation by repression of Aurora B in hepatocellular carcinoma cells The Inner Centromere Protein (INCENP) Coil Is a Single α-Helix (SAH) Domain That Binds Directly to Microtubules and Is Important for Chromosome Passenger Complex (CPC) Localization and Function in Mitosis.Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation SUMOylation modulates the function of Aurora-B kinase Targeting the INCENP IN-box-Aurora B interaction to inhibit CPC activity in vivo.The chromosomal passenger complex (CPC) as a key orchestrator of orderly mitotic exit and cytokinesis.Ipl1/Aurora-dependent phosphorylation of Sli15/INCENP regulates CPC-spindle interaction to ensure proper microtubule dynamics.Aurora B dynamics at centromeres create a diffusion-based phosphorylation gradient.Geminin overexpression induces mammary tumors via suppressing cytokinesis.Aurora B is regulated by acetylation/deacetylation during mitosis in prostate cancer cells.Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast.The chromatin remodeller RSF1 is essential for PLK1 deposition and function at mitotic kinetochores.The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis.Overexpression of Aurora-C interferes with the spindle checkpoint by promoting the degradation of Aurora-B.PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.Aurora kinases orchestrate mitosis; who are the players?Aurora B expression modulates paclitaxel response in non-small cell lung cancer.p21Waf1/Cip1 deficiency causes multiple mitotic defects in tumor cells.Use of DT40 conditional-knockout cell lines to study chromosomal passenger protein function.Gradient of increasing Aurora B kinase activity is required for cells to execute mitosis Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase Binucleine 2, an isoform-specific inhibitor of Drosophila Aurora B kinase, provides insights into the mechanism of cytokinesis High-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis.Sgo1 as a "guardian spirit" for preventing colon tumorigenesis.RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility.The Ins and Outs of Aurora B Inner Centromere Localization.Seh1 targets GATOR2 and Nup153 to mitotic chromosomes.Mutation screening of AURKB and SYCP3 in patients with reproductive problems.Polymorphisms in and are associated with the survival of triple-negative breast cancer patients treated with taxane-based adjuvant chemotherapy

P2860

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P2860

INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization.

http://www.wikidata.org/entity/Q33590962

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

INCENP-aurora B interactions m ...... assenger complex localization.

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INCENP-aurora B interactions m ...... assenger complex localization.

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type

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INCENP-aurora B interactions m ...... assenger complex localization.

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INCENP-aurora B interactions m ...... assenger complex localization.

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INCENP-aurora B interactions m ...... assenger complex localization.

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INCENP-aurora B interactions m ...... assenger complex localization.

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Journal of Cell Biology

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INCENP-aurora B interactions m ...... assenger complex localization.

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P2093

Damien F Hudson

http://www.w3.org/2001/XMLSchema#string

Hiromi Ogawa

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Jan H Bergmann

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Kumiko Samejima

http://www.w3.org/2001/XMLSchema#string

Paola Vagnarelli

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Sandrine Ruchaud

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Tatsuo Fukagawa

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Zhenjie Xu

http://www.w3.org/2001/XMLSchema#string

P2860

INCENP centromere and spindle targeting: identification of essential conserved motifs and involvement of heterochromatin protein HP1

Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together

The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly

Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension

The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint

CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore

Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody

Recruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cells

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637-653

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scholarly article

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10.1083/JCB.200906053

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P433

5

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187

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William Charles Earnshaw

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2009-11-01T00:00:00Z

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40045000

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19951914

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2806593

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