Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma. - Test2 - elhamkhani - TriplyDB

Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma.

Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma.

http://www.wikidata.org/entity/Q33592374

about

SIBLINGs and SPARC families: their emerging roles in pancreatic cancer Metastatic pancreatic cancer: Is there a light at the end of the tunnel?Preventing effects of joint contracture by high molecular weight hyaluronan injections in a rat immobilized knee model.Loss of SPARC in bladder cancer enhances carcinogenesis and progression.Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.Proangiogenic scaffolds as functional templates for cardiac tissue engineering.SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice.Pancreatic biomarkers: could they be the answer?Chemotherapy and tumor microenvironment of pancreatic cancer.Impact of tumour associated macrophages in pancreatic cancer.Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation.A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells.Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.Stromal disrupting effects of nab-paclitaxel in pancreatic cancer LPS induces greater bone and PDL loss in SPARC-null mice SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity.SPARC Controls Melanoma Cell Plasticity through Rac1.Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization.The role of SPARC protein expression in the progress of gastric cancer.Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke.Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib.Overexpression of SPARC in human trabecular meshwork increases intraocular pressure and alters extracellular matrix BIBF 1120 (nintedanib), a triple angiokinase inhibitor, induces hypoxia but not EMT and blocks progression of preclinical models of lung and pancreatic cancer.Tumor-associated macrophages as incessant builders and destroyers of the cancer stroma.Roles of SPARC in urothelial carcinogenesis, progression and metastasis.Collagen as a double-edged sword in tumor progression.Dynamic interplay between the collagen scaffold and tumor evolution.Forcing form and function: biomechanical regulation of tumor evolution.The regulatory function of SPARC in vascular biology.Stromal expression of SPARC in pancreatic adenocarcinoma.Recruitment and retention: factors that affect pericyte migration.Molecular mechanisms underlying the divergent roles of SPARC in human carcinogenesis.Cancer-associated fibroblasts in pancreatic adenocarcinoma.Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma.Matricellular proteins osteopontin and osteonectin/SPARC in pancreatic carcinoma.Decorin gene upregulation mediated by an adeno-associated virus vector increases intratumoral uptake of nab-paclitaxel in neuroblastoma via inhibition of stabilin-1.Proteolytic Isoforms of SPARC Induce Adipose Stromal Cell Mobilization in Obesity.Hypoxia Studies with Pimonidazole in vivo.SPARC expression in resected pancreatic cancer patients treated with gemcitabine: results from the CONKO-001 study.Mammary epithelium-specific inactivation of V-ATPase reduces stiffness of extracellular matrix and enhances metastasis of breast cancer.

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Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma.

http://www.wikidata.org/entity/Q33592374

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Lack of host SPARC enhances va ...... model of pancreatic carcinoma.

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Lack of host SPARC enhances va ...... model of pancreatic carcinoma.

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Lack of host SPARC enhances va ...... model of pancreatic carcinoma.

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Lack of host SPARC enhances va ...... model of pancreatic carcinoma.

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Lack of host SPARC enhances va ...... model of pancreatic carcinoma.

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Lack of host SPARC enhances va ...... model of pancreatic carcinoma.

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Disease Models & Mechanisms

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Lack of host SPARC enhances va ...... model of pancreatic carcinoma.

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P2093

Amy D Bradshaw

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Andrew F Miller

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Diego H Castrillon

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E Helene Sage

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Juliet G Carbon

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Lee B Rivera

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Pauli Puolakkainen

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Rolf A Brekken

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Shanna A Arnold

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Yang Xie

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P2860

Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin

Osteonectin influences growth and invasion of pancreatic cancer cells

The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix

Human endomucin is an endothelial marker

Biochemical characterization and molecular cloning of a novel endothelial-specific sialomucin

Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

The role of myeloid cells in the promotion of tumour angiogenesis

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57-72

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10.1242/DMM.003228

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1-2

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3

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40685244

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20007485

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2806901

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