Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing.
about
Computational delineation of tyrosyl-substrate recognition and catalytic landscapes by the epidermal growth factor receptor tyrosine kinase domain.Role of network branching in eliciting differential short-term signaling responses in the hypersensitive epidermal growth factor receptor mutants implicated in lung cancerAtomistic insights into regulatory mechanisms of the HER2 tyrosine kinase domain: a molecular dynamics study.Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases.A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling networkStructural systems biology and multiscale signaling models.Dynamic transition states of ErbB1 phosphorylation predicted by spatial stochastic modelingMultiscale cancer modelingMolecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype.Personalized medicine approaches for colon cancer driven by genomics and systems biology: OncoTrackMolecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinasesLink synthetic lethality to drug sensitivity of cancer cells.
P2860
Q30581942-EAF9F546-1255-4EBA-9AC7-4FD29F0F6169Q33576845-D4D600CA-0165-4673-84FA-8A6A35A0E79BQ34010366-483412E4-DC52-4FBC-AEBC-D91301A39F15Q35058437-653105B0-8B36-4388-BCEE-C7FFD1ED79C7Q35111697-41C6989B-5325-4837-9F8B-556DDA988119Q36181814-F65BCC8F-3BC9-4658-962B-2AE0779BC1C2Q37204361-C317A0D6-5590-4BD5-80FA-3D2712F72ABFQ37443767-96F006FB-D9E3-4281-A355-2672ED6C528BQ37602884-C7D393AF-0D10-4686-B92C-26DB02A41C52Q38235205-E4A5E1DD-5FBA-4BC5-A494-D695E8B74046Q42822469-952228C5-6C79-495D-A89B-16C188A9E19DQ47209937-CBD1BAC3-C2B5-4F6F-9E3A-C0389EA44BB0
P2860
Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing.
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Molecular systems biology of E ...... nd high-performance computing.
@ast
Molecular systems biology of E ...... nd high-performance computing.
@en
type
label
Molecular systems biology of E ...... nd high-performance computing.
@ast
Molecular systems biology of E ...... nd high-performance computing.
@en
prefLabel
Molecular systems biology of E ...... nd high-performance computing.
@ast
Molecular systems biology of E ...... nd high-performance computing.
@en
P2093
P2860
P356
P1433
P1476
Molecular systems biology of E ...... nd high-performance computing.
@en
P2093
Andrew J Shih
Jeremy Purvis
Ravi Radhakrishnan
P2860
P304
P356
10.1039/B803806F
P577
2008-09-12T00:00:00Z